Results 91 to 100 of about 136,291 (302)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Preparation and characterization of silymarin synchronized-release microporous osmotic pump tablets
Drug Design, Development and Therapy, 2016 Qi-ping Zeng,* Zhi-hong Liu,* Ai-wen Huang, Jing Zhang, Hong-tao Song Department of Pharmacy, Fuzhou General Hospital of Nanjing Command PLA, Fuzhou, People’s Republic of China *These authors contributed equally to this work Abstract: The ...
Zeng QP +4 more
doaj
Determination and validation of secnidazole in tablets by UV spectrophotometric
Bioscience Journal, 2017 Secnidazole, a 5-nitroimidazole, is a drug used in the treatment against protozoa, and several bacterial infections. This study purpose was to develop and validate a UV spectrophotometric method to determine secnidazole in pharmaceutical tablet dosage ...
Márcia Regina Marcílio +6 more
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Sensors, 2016 A potentiometric electronic tongue was applied to study the release of valsartan from pharmaceutical formulations, i.e., minitablets uncoated and coated with Eudragit E.
Małgorzata Wesoły +4 more
doaj +1 more source
In Vivo Relevance of a Biphasic In Vitro Dissolution Test for the Immediate Release Tablet Formulations of Lamotrigine. [PDF]
Pharmaceutics, 2023 Incecayir T, Demir ME.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
An Examination of Subsidence in North-East England due to the Dissolution of Sub-Surface Gypsum using the Shallow Seismic Reflection Technique [PDF]
, 2009 Along a narrow swath from Nottingham through to Hartlepool, broad shallow depressions up to 100m in diameter and, more rarely, scarp-edged subsidence hollows are observed.
Sargent, Colin
core
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Testing for Multivariate Equivalence with Random Quadratic Forms [PDF]
Multivariate equivalence testing becomes necessary whenever the similarity rather than a difference between several treatment groups with multiple endpoints has to be shown.
Weißbach, Rafael
core