Results 81 to 90 of about 136,291 (302)
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evaluation of Glass Dissolution Vessel Dimensions and Irregularities
, 2007 Used in the private or public USP Performance test,dissolution testing plays an important role in bothproduct development and quality assurance for nonsolution oral dosage forms.
Samir Z. Wahab +5 more
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APPLICATION OF MATHEMATICAL MODELING IN THE EVALUATION OF IN VITRO DRUG RELEASE
Разработка и регистрация лекарственных средств, 2019 Descriptions of mathematical models using for drug dissolution studying from modified-release systems (zero-order kinetic, first-order kinetic, Weibull model, Hixon - Crowell model, Higuchi model, Baker - Lonsdale model, Hopfenberg model, Gompertz model,
N. I. Filippova, A. A. Teslev
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Comparison of the Rupture and Disintegration Tests for Soft-Shell Capsules
, 2011 The USP General Chapter < 2040 > Disintegration and Dissolution of Dietary Supplements introduced a rupture test as a performance test of soft-shell capsules.
ALMUKAINZI, May +3 more
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SCIENTIFIC-METHODICAL APPROACHES AND RESULTS OF THE PHARMACEUTICAL DEVELOPMENT OF SUPPOSITORIES
Разработка и регистрация лекарственных средств, 2019 In article theoretical and practical results of longstanding work of collective of Pharmaceutical technology department of Kursk State Medical University for the development of rectal and vaginal suppositories for the treatment of infectious and ...
T. A. Pankrusheva +4 more
doaj
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Perturbation Study of Dissolution Apparatus Variables—A Design of Experiment Approach
, 2007 For nonsolution,orally administered dosage forms,theUSP Performance test can rely on either disintegration(General Chapter Disintegration <701>) or dissolution (General Chapter Dissolution <711>).
William Brown +5 more
core
Química Nova, 2011 This work describes the establishment of dissolution test conditions for 75 mg cinnarizine capsules using a multivariate approach. A 2³ full factorial design was carried out to achieve the best conditions and HCl 0.1 mol L-1 as dissolution medium, basket
Patrícia Alves Franco Gehring +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source