Results 71 to 80 of about 6,915,672 (299)
, 2011 The Biopharmaceutics Classification System (BCS) is a tool that was created to categorize drugs into different groups according to their solubility and permeability characteristics.
ISSA, Michele G., FERRAZ, Humberto G.
core
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 The results of Indomethacin release from the oral drug delivery systems based on interpolymer complexes with Eudragit® copolymers are presented.
A. V. Sitenkova (Bukhovets) +2 more
doaj
The Journal of Reproduction and DevelopmentProgesterone (P4)-impregnated controlled internal drug-releasing device for goats and sheep (CIDR-G) is used in the estrus synchronization protocol; however, it is not commercially available in Japan. In this study, we investigated whether a modification
Kotaro SAITO +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
THE FEATURES OF THE PREDICTIVE DISSOLUTION TESTING (REVIEW)
Разработка и регистрация лекарственных средств, 2019 Dissolution test plays an important role at different levels of the development and manufacturing drugs as one of the major quality control tools and an integral part of In vitro tests in the study of drug release from the developed dosage forms. Article
R. I. Moustafine +2 more
doaj
Development and Laboratory Test of All-Metal Bridge Plug for Ultra-High Temperature Environments
Shiyou jixie, 2023 Soluble bridge plugs are deficient for low compressive strength,slow degradation rate,and inapplicability to ultra-high temperature environment.For these problems,an innovative design of all-metal bridge plug for ultra-high temperature environments was ...
Cheng Yuxiong +5 more
doaj
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
APPLICATION OF MATHEMATICAL MODELING IN THE EVALUATION OF IN VITRO DRUG RELEASE
Разработка и регистрация лекарственных средств, 2019 Descriptions of mathematical models using for drug dissolution studying from modified-release systems (zero-order kinetic, first-order kinetic, Weibull model, Hixon - Crowell model, Higuchi model, Baker - Lonsdale model, Hopfenberg model, Gompertz model,
N. I. Filippova, A. A. Teslev
doaj
PCS-Q-G. Parental Caregiving Style Questionnaire – German Version
Der PCS-Q-G dient der retrospektiven Erfassung des elterlichen Fürsorgeverhaltens. In Analogie zum 3-Kategorien-Modell von Bindung unterscheidet das Instrument zwischen den drei Stilen „warm/aufmerksam“, „ambivalent/inkonsistent“ und „kalt/abweisend ...
Rohmann, E., Neumann, E.
core +1 more source