Results 61 to 70 of about 1,822,931 (347)

Cost-effectiveness analysis of the management of distal ureteral stones in children [PDF]

open access: yes, 2019
Objective To determine the most cost-effective approach to the management of distal ureteral stones in children given the potential for recurrent renal colic during a trial of passage versus potential stent discomfort and complications of ureteroscopy.
Bennett, William E., Jr.   +6 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Pediatric distal metaphysis fractures of the humerus: etiopathogenesis, clinical features, diagnostics, treatment

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Backgrоund. Distal metaphysis fractures of the humerus in children are the most common among elbow joint injuries in children, occurring in 64–70%. Aim.
O. N. Amairi   +3 more
doaj   +1 more source

The Effect of Balsamic Vinegar Dressing on Protein and Carbohydrate Digestibility is Dependent on the Food Matrix

open access: yesFoods, 2021
The balsamic vinegar of Modena (BVM), a food specialty under the European Protected Geographical Indication system, is made from grape must blended with wine vinegar exclusively in the Italian province of Modena or Reggio Emilia. Vinegar is associated to
Eleonora Urbinati   +5 more
doaj   +1 more source

Joint interpretation of AER/FGF and ZPA/SHH over time and space underlies hairy2 expression in the chick limb [PDF]

open access: yes, 2012
Embryo development requires precise orchestration of cell proliferation and differentiation in both time and space. A molecular clock operating through gene expression oscillations was first described in the presomitic mesoderm (PSM) underlying periodic ...
Andrade, Raquel P.   +2 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

QTL mapping identifies novel major loci for kernel row number-associated ear fasciation, ear prolificacy and tillering in maize (Zea mays L.)

open access: yesFrontiers in Plant Science, 2023
Maize ear fasciation originates from excessive or abnormal proliferation of the ear meristem and usually manifests as flattened multiple-tipped ear and/or disordered kernel arrangement.
Kai Li   +6 more
doaj   +1 more source

Posterolateral Elbow Dislocation with Ipsilateral Fractures of Head and Distal End Radius [PDF]

open access: yes, 2011
Elbow dislocation associated with ipsilateral fracture head and distal end radius is a rare pattern of Injury, although it is common for elbow dislocation and radius fractures to occur separately.
C, Vijay   +3 more
core   +1 more source

Distal Convoluted Tubule [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2014
The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule ...
Arohan R, Subramanya, David H, Ellison
openaire   +2 more sources

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