Results 111 to 120 of about 3,907,799 (305)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Running head: PHONOLOGICAL DISTANCE MEASURES Phonological Distance Measures

open access: yes, 2008
Phonological distance measures 2 Phonological distance can be measured computationally using formally specified algorithms. This work investigates two such measures, one developed by Nerbonne and Heeringa (1997) based on Levenshtein distance (Levenshtein,
Nathan C Sanders   +2 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

NPS Distance Learning Curricula [PDF]

open access: yes, 2014
The following courses are available through Distance Learning. Normal academic requirements, admissions procedures, and funding requirements apply. At the current time individual courses within degree or certificate programs are not available as stand ...

core   +1 more source

On distance preserving and sequentially distance preserving graphs

open access: yesThe Art of Discrete and Applied Mathematics
A graph $H$ is an \emph{isometric} subgraph of $G$ if $d_H(u,v)= d_G(u,v)$, for every pair~$u,v\in V(H)$. A graph is \emph{distance preserving} if it has an isometric subgraph of every possible order. A graph is \emph{sequentially distance preserving} if its vertices can be ordered such that deleting the first $i$ vertices results in an isometric ...
Jason P. Smith, Emad Zahedi
openaire   +4 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Effective partnerships in Open Distance Learning: implications of the Irish National Distance Education Centre model [PDF]

open access: yes, 1998
The National Distance Education Centre in Ireland has adopted a cooperative and collaborative approach in meeting its primary aim of extending access to qualifications and training throughout Ireland to those who are unable to attend full-time education ...
MacKeogh, Kay
core   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The world of learning

open access: yesJournal of Open, Flexible and Distance Learning, 2012
Column about conferences events and new publications in distance learning.
Glenise Dreaver, Terry Hearn
doaj   +2 more sources

Distance-regular Subgraphs in a Distance-regular Graph, IV

open access: yesEuropean Journal of Combinatorics, 1995
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +7 more sources

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