Results 41 to 50 of about 4,557,374 (284)

Learning quantum data with the quantum earth mover’s distance [PDF]

open access: hybrid, 2022
Bobak T. Kiani   +4 more
openalex   +1 more source

QMEANDisCo—distance constraints applied on model quality estimation

open access: yesBioinform., 2019
Motivation Methods that estimate the quality of a 3D protein structure model in absence of an experimental reference structure are crucial to determine a model’s utility and potential applications.
G. Studer   +5 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Learners and E-Tutors Experiences of Authentic Assessment in Babcock University Centre for Open Distance and e-Learning

open access: yesWest African Journal of Open and Flexible Learning, 2022
Authentic Assessment (AA) has been heralded as the form of assessment that reflects the real world in classroom learning. Recognising this, the Commonwealth of Learning (COL), in collaboration with the National Universities Commission (NUC) in Nigeria ...
Mobolanle Ebunoluwa Sotunsa   +4 more
doaj  

FastME 2.0: A Comprehensive, Accurate, and Fast Distance-Based Phylogeny Inference Program

open access: yesMolecular biology and evolution, 2015
FastME provides distance algorithms to infer phylogenies. FastME is based on balanced minimum evolution, which is the very principle of Neighbor Joining (NJ).
Vincent Lefort, R. Desper, O. Gascuel
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Wasserstein Distance Guided Representation Learning for Domain Adaptation

open access: yesAAAI Conference on Artificial Intelligence, 2017
Domain adaptation aims at generalizing a high-performance learner on a target domain via utilizing the knowledge distilled from a source domain which has a different but related data distribution.
Jian Shen   +3 more
semanticscholar   +1 more source

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