Results 91 to 100 of about 8,115,379 (305)

Cradle to Cradle of Sanitation Value Chain, George Compoun, Lusaka Zambia: A Stakeholder Perspective

open access: yesJournal of Arts, Humanities and Social Science
The study explored sanitation value chain from cradle to cradle in George Compound, Lusaka, Zambia. The study uncovered that pit latrines constructed under the Lusaka sanitation program followed the standard procedures, whereas those constructed by most
James Mwale   +3 more
doaj   +1 more source

Students’ Opinions about the Distance Education to Art and Design Courses in the Pandemic Process

open access: yesWorld Journal of Education, 2020
This research was carried out to determine student views on distance education through art and design courses. The study group of the research consists of 45 undergraduate students studying at different faculties of İzmir Katip Çelebi University in ...
Sehran Dilmaç
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

College Students’ Views on the Pandemic Distance Education: A Focus Group Discussion

open access: yes, 2020
The COVID-19 is a deadly pandemic that has affected every aspect of life including education. The schools have been closed to prevent the spread of the virus, and they have converted their system into distance education.
Seçil Tümen Akyıldız
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Scale-Up Considerations of the Sundial Rotating Fresnel Solar Collector

open access: yesSolarPACES Conference Proceedings
In the frame of the ASTEP project two prototypes of the Sundial collector, together with a Phase Change Material Thermal Energy Storage, will be tested integrated with the industrial processes of two sites.
Mercedes Ibarra   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Exploring students’ experiences with authentic assessment in an online learning context

open access: yesInternational Journal of Educational Management and Development Studies
Authentic assessment brings a new dimension to assessment where learning and assessment are linked to genuine workplace environments. In this assessment, students apply knowledge and skills to solve real and felt workplace problems.
Cosmas Maphosa   +2 more
doaj   +1 more source

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