Results 71 to 80 of about 10,062,431 (307)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

An Appropriateness of Primary School Teachers’ Pedagogical Skills for Teaching The 2023 Curriculum in Chongwe District, Zambia

open access: yesJournal of Arts, Humanities and Social Science
The study sought to describe the appropriateness of primary school teachers’ pedagogical skills for teaching the 2023 curriculum in Chongwe District.
Pamela Kabwali   +3 more
doaj   +1 more source

Virtual Leadership at Distance Education Teams [PDF]

open access: yes, 2016
Globalization being one of the most popular terms of recent years is considered as a factor changing the operation styles of the companies. Companies and universities opened up to the world with the globalization and as a result of it, they had the ...
Arslan, Hasan, Kuscu, Meltem
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Cradle to Cradle of Sanitation Value Chain, George Compoun, Lusaka Zambia: A Stakeholder Perspective

open access: yesJournal of Arts, Humanities and Social Science
The study explored sanitation value chain from cradle to cradle in George Compound, Lusaka, Zambia. The study uncovered that pit latrines constructed under the Lusaka sanitation program followed the standard procedures, whereas those constructed by most
James Mwale   +3 more
doaj   +1 more source

Exploring the use of distance education technology for lifestyle change

open access: yes, 2011
Obesity affects over 100 million men, women, and children in North America alone and has reached what health professionals deem to be epidemic proportions.
Patrick J. Tierney
core  

Looking to the future ... Distance Education Issues in Nebraska [PDF]

open access: yes, 2000
The Nebraska Network 21 (NN21) Action Team on Distance Education/Outreach has studied a variety of issues related to distance education in order to better serve the people of Nebraska.
Action Team, NN21 Distance Education/Outreach
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Acquisition of Soft Skills and Affective Outcomes in Online Distance Education: A Secondary School Study

open access: yes, 2008
Canada is facing a shortage of workers skilled in affective outcomes, specifically soft skills. Some fingers are pointing to the primary and secondary institutions for failing to aptly prepare future employees with those skills.
Hertlein, J. L.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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