Results 41 to 50 of about 442,809 (277)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Using Web-Based, Group Communication Systems to Support Case Study Learning at a Distance
International Review of Research in Open and Distributed Learning, 2002 This study explored the capacity of Web-based, group communication systems to support case-based teaching and learning. Eleven graduate students studying at a distance were divided into three groups to collaborate on a case study using either a ...
Liam Rourke +1 more
doaj
Journal of Arts, Humanities and Social ScienceSanitation interventions in most peri-urban areas are being implemented without taking into consideration the special needs for the people living with vulnerabilities. In most cases, the sanitation technologies and designs are being developed without buy
James Mwale +3 more
doaj +1 more source
Online professional development conferences: An effective, economical and eco-friendly option
Canadian Journal of Learning and Technology, 2010 In order to stay current within their field, many professionals regularly attend conferences and training events in distant locales. Travel to these conferences costs professionals, and their sponsor organizations, both time and money.
Lynn Anderson, Terry Anderson
doaj +1 more source
The relative importance of distance education challenges to instructors in higher education – A ranking-type Delphi study [PDF]
, 2023 Henrik Sällberg, Emil Folino
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Australian and International Journal of Rural Education, 2008 Distance education is becoming a more common method of curriculum delivery across grade levels in Australia, the United States and throughout the world. Especially in remote rural areas with sparse student populations, distance delivery of course work is often the only available means for students to learn and for teachers to teach.
openaire +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
International Journal for Innovation Education and Research, 2018 This article presents a new tool to be used in distance learning courses: Structured Knowledge Maps. The method is best adapted to what one wants to teach/transmit (explicit/tacit knowledge), personalizing the didactic material to the student and equalizing the necessary knowledge for all the learners in the same class, that is, if the student ...
Thales Oliveira Lima +2 more
openaire +3 more sources