Results 41 to 50 of about 9,626,056 (303)

Challenges and contexts in establishing adaptive learning in higher education: findings from a Delphi study

International Journal of Educational Technology in Higher Education, 2020
Higher education institutions are increasingly interested in using adaptive learning as an innovative data-driven approach to teaching. The actual use of adaptive learning in courses remains, however, low.
Victoria Mirata, Franziska Hirt, Per Bergamin, Christo van der Westhuizen   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Editorial ~ Open Access in Action!

International Review of Research in Open and Distributed Learning, 2006
Mid 2006 finds the academic research community engaged in an ideological and fiscal war related to Open Access publishing. Open Access requires that the full text of publications be made available at no cost to anyone on the open Internet.
Terry Anderson, Canada Research Chair in Distance Education
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Using Virtual Worlds in Distance Education [PDF]

, 2017
This case study examines the effectiveness of 3D Virtual Worlds (VWs) in Distance Education (DE). A series of in-world collaborative learning activities (4 in total) was conducted in the virtual world of Second Life (SL) with 9 DE students from Athabasca
Nteliopoulou, Sofia
core  

Education of women and women's expectations from distance education on the issues concerning them [PDF]

, 2014
The most important factor that enables women to become individuals in society is education. It is also a very crucial part of rectifying the circumstances they are in.
Demiray, Emine
core   +1 more source

Using Web-Based, Group Communication Systems to Support Case Study Learning at a Distance

International Review of Research in Open and Distributed Learning, 2002
This study explored the capacity of Web-based, group communication systems to support case-based teaching and learning. Eleven graduate students studying at a distance were divided into three groups to collaborate on a case study using either a ...
Liam Rourke, Terry Anderson, Canada Research Chair in Distance Education   +1 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Disability Friendly Sanitation Facilities in George Compound in Lusaka, Zambia: A Stakeholders Perspective

Journal of Arts, Humanities and Social Science
Sanitation interventions in most peri-urban areas are being implemented without taking into consideration the special needs for the people living with vulnerabilities. In most cases, the sanitation technologies and designs are being developed without buy
James Mwale, Vincent Kanyamuna, John Moose, Francis Simui   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source