Results 41 to 50 of about 10,062,431 (307)

“Spray Technique: Tracing the Sketch Traditions of Limestone Cave in Lenggong, Perak”

open access: yesSHS Web of Conferences, 2015
Archaeological research provides the widest opportunity for researchers to analyse various aspects and disciplines appropriate to the subject and the object of choice.
Yahaya Fatan Hamamah   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Editorial ~ CIDER is Born

open access: yesInternational Review of Research in Open and Distributed Learning, 2004
With significant male trepidation, I want to share a birth story with IRRODL readers. This month, after a seemingly endless gestation, the Canadian Institute for Distance Education Research (CIDER) was born. Like most births, this new presence began with
Terry Anderson, Canada Research Chair in Distance Education
doaj  

Coping with burnout: analysis of linear, non-linear and interaction relationships

open access: yesAnales de Psicologia, 2017
This study analyzes the relationship between action-focused coping, emotion-focused coping and burnout dimensions (emotional exhaustion, cynicism and personal accomplishment) by comparing linear, non-linear and interaction models using quadratic ...
José A. García-Arroyo, Amparo Osca
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Book Review ~ Delivering Digitally: Managing the transition to the knowledge media. Edited by A. Inglis, P. Ling, and V. Joosten

open access: yesInternational Review of Research in Open and Distributed Learning, 2002
We know that significant organizational change must have roots both at the top of an organization and “in the trenches” amongst those who must implement the change.
Terry Anderson, Canada Research Chair in Distance Education
doaj  

Challenges and contexts in establishing adaptive learning in higher education: findings from a Delphi study

open access: yesInternational Journal of Educational Technology in Higher Education, 2020
Higher education institutions are increasingly interested in using adaptive learning as an innovative data-driven approach to teaching. The actual use of adaptive learning in courses remains, however, low.
Victoria Mirata   +3 more
doaj   +1 more source

Sixty-six years of a guidance service delivery in Ghana: Analysis of stakeholders' attitudes and perceived relevance on career success

open access: yesCogent Education, 2023
This study examined 66 years of guidance service delivery in Ghana by analysing stakeholders’ attitudes and perceived relevance to career success. The study employed positivist philosophy and cross-sectional survey methods.
Moses Segbenya   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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