Results 91 to 100 of about 3,101,401 (288)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Aura, Self, and Aesthetic Experience

open access: yesContemporary Aesthetics, 2011
Aesthetic experiences are generated in encounters with cultural objects and such experiences are marked by the free play of cognitive and numinous experience unstructured by concepts.
Marshall Battani
doaj  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Application of the equality and non-discrimination principles for migrants workers [PDF]

open access: yesCivilizar, 2012
The principle of equality and non-discrimination is considered one of the main pillars and inspiring in most international instruments on human rights protection.
María Teresa Palacios Sanabria
doaj  

Anachronisme et humour : de l’usage intempestif de l’anachronisme dans la fiction en costumes

open access: yesMise au Point, 2017
After defining anachronism as a rhetorical process, this article aims to highlight its humorous effects - particularly untimely in the diegetic universe where one a priori expects the least: historical fiction .
Bernard Papin
doaj   +1 more source

What is ‘mental action’? [PDF]

open access: yes, 2019
There has been a resurgence of interest lately within philosophy of mind and action in the category of mental action. Against this background, the present paper aims to question the very possibility, or at least the theoretical ...
Levy, Yair
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Les «Amériques Noires» de Roger Bastide: un modèle pour une analyse anthropologique des styles de vie

open access: yesHorizontes Antropológicos, 2010
Le nom de Roger Bastide est généralement associé à la sociologie des religions du Brésil. On peut cependant trouver dans son œuvre un paradigme pertinent pour une analyse anthropologique des styles de vie.
Michel Daccache
doaj   +1 more source

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