Results 101 to 110 of about 3,102,738 (289)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Identification of Three Dalbergia Species Based on Differences in Extractive Components

open access: yesMolecules, 2018
Dalbergia cultrate, Dalbergia latifolia, and Dalbergia melanoxylon are precious and valuable traded timber species of the genus Dalbergia. For chemotaxonomical discrimination between these easily confused species, the total extractive content of the ...
Xiaoqian Yin   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

L'invention de distinction, moteur du tourisme? Hier et aujourd'hui

open access: yesTéoros, 1995
Vers 1950-1960, quand commençaient mes recherches, la réflexion épistémologique sure le loisir et le tourisme étai à ses débuts. Les Français ne connurent Th. Veblen qu’après sa traduction; J.
Marc Boyer
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Mujeres de coto en Guadalajara, Jalisco

open access: yesAmerika, 2013
This text discusses how the gated communities of the upper class spatial logic makes sense approaching their styles of life through the voices of women who reside in them.
Manuela Camus Bergareche
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The nobiliary concept of play as a mechanism for ethical-political distinction in the Late Middle Ages. (El imaginario lúdico de la nobleza como dispositivo de la distinción ético-política en la Baja Edad Media Occidental). [PDF]

open access: yesRevista Internacional de Ciencias del Deporte, 2008
This article examines the problematic meaning, both in concept and practice, of games in the late Middle Ages, using Norbert Elias’ theoretical perspective of the civilizing process.
Manuel Rodríguez López   +1 more
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

KANT’IN TEORİK AKIL-PRATİK AKIL AYRIMINA ELEŞTİREL BİR YAKLAŞIM

open access: yesFelsefe Dünyası, 2020
Kant’ın düşünce sistemi hissetme ile düşünme yetileri arasında yaptığı ayrım üzerinde yükselir. Bu ayrım Kant tarafından temellendirilmemiştir; sistemin bütünü bakımından bir hipotez niteliğindedir.
Aliye Kovanlıkaya
doaj  

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