Results 131 to 140 of about 3,102,738 (289)
Meadian reflections on the existential ambivalence of human selfhood [PDF]
, 2010 This paper examines the existential ambivalence of human selfhood by drawing upon George Herbert Mead’s distinction between the ‘I’ and the ‘me’. In order to make a case for the centrality of this conceptual distinction, the paper offers a comprehensive
Susen, Simon
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Law’s Symbolic Power: Beyond the Marxist Conception of Ideology
Wroclaw Review of Law, Administration and Economics, 2016 Dębska Hanna
doaj +1 more source
Cogitatio e Res cogitans. La genesi della distinzione fra sostanza e attributo principale
Lexicon PhilosophicumQuesto articolo ritorna sulla dibattuta questione dei rapporti fra sostanza ed attributo principale proponendo un approccio diacronico per la sua soluzione e, segnatamente, individuando nelle Tertiae responsiones la genesi della suddetta distinzione ...
Igor Agostini
doaj +1 more source
(WP 2017-04) Behavioral Economics and the Positive-Normative Distinction: Sunstein’s \u3cem\u3eChoosing Not to Choose\u3c/em\u3e and Behavioral Economics Imperialism [PDF]
, 2017 This paper examines behavioral economics’ use of the positive-normative distinction in its critique of standard rational choice theory as normative, and argues that it departs from Robbins’ understanding of that distinction in ways that suggest ...
Davis, John B.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source