Results 41 to 50 of about 26,832 (297)

RETRACTED: An improved DBSCAN algorithm based on cell-like P systems with promoters and inhibitors.

open access: yesPLoS ONE, 2018
Density-based spatial clustering of applications with noise (DBSCAN) algorithm can find clusters of arbitrary shape, while the noise points can be removed.
Yuzhen Zhao, Xiyu Liu, Xiufeng Li
doaj   +1 more source

Distributed and Parallel Systems Cluster and Grid Computing

open access: yes, 2002
Distributed and Parallel Systems: Cluster and Grid Computing is the proceedings of the fourth Austrian-Hungarian Workshop on Distributed and Parallel Systems organized jointly by Johannes Kepler University, Linz, Austria and the MTA SZTAKI Computer and ...
Nemeth, Zsolt 1971-   +3 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Distributed Load-Balancing Method for CCA Parallel Component Applications

open access: yesAlgorithms
Numerous universities and national laboratories in the United States have collaboratively established a Common Component Architecture (CCA) forum to conduct research on parallel component technology.
Lei Guo, Xin Guo, Feiya Lv
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Hadoop bottleneck detection algorithm based on information gain

open access: yesDianxin kexue, 2016
Hadoop has become a major platform for big data storage and large data mining nowadays.Although Hadoop platform achieves high performance parallel computing through a distributed cluster of machines,the bottlenecks will inevitably appear on a machine ...
Zaole TAN   +4 more
doaj   +2 more sources

Programming Distributed Collective Processes in the eXchange Calculus [PDF]

open access: yesLogical Methods in Computer Science
Recent trends like the Internet of Things (IoT) suggest a vision of dense and multi-scale deployments of computing devices in nearly all kinds of environments.
Giorgio Audrito   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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