Results 51 to 60 of about 26,080 (290)

Parallel Implementation and Scalability Results of a Local-Scale Air Quality Model: Application to Bamako Urban City

Journal of Applied Mathematics, 2022
We present a computational framework for the parallel implementation of a local-scale air quality model described by an advection-diffusion-reaction partial differential equation, the so-called equation of reactive dispersion. The temporal discretization
Abdoulaye Samaké, Amadou Mahamane, Ouaténi Diallo   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Evaluation of a small scale cluster computing system for parallel intelligent techniques applications [PDF]

, 2005
A small scale distributed computing system that is able to meet the needs of parallel intelligent techniques for engineering and science applications is reported in this paper.
Myers, D., Li, J.B., Fung, C.C.
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

An Improved K-means Distributed Clustering Algorithm Based on Spark Parallel Computing Framework

Journal of Physics: Conference Series, 2020
Abstract Traditional K-means distributed clustering algorithm has many problems in clustering big data, such as unstable clustering results, poor clustering results and low execution efficiency. In this paper, a density based initial clustering center selection method is proposed to improve the K-means distributed clustering algorithm ...
Xin Lu, Huanghuang Lu, Jiao Yuan, Xun Wang   +3 more
openaire   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

STRUCTURAL SYSTEM SIMULATION USING GRID-COMPUTING FRAMEWORK

Journal of Civil Engineering
A multi-level modeling and simulation method of structural system using grid-computing framework is proposed in this paper. Two levels of parallel processing will be involved in this framework: (1) multiple locally distributed computing environments ...
Data Iranata, Radityo Anggoro
doaj   +1 more source

A Framework for Certified Self-Stabilization [PDF]

Logical Methods in Computer Science, 2017
We propose a general framework to build certified proofs of distributed self-stabilizing algorithms with the proof assistant Coq. We first define in Coq the locally shared memory model with composite atomicity, the most commonly used model in the self ...
Karine Altisen, Pierre Corbineau, Stephane Devismes   +2 more
doaj   +1 more source