Results 51 to 60 of about 3,487,111 (248)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Fault Tolerant Distribiuted Algorithms and VLSI - An Appetizer

, 2009
From September the $7^{\text{th}}$, 2008 to September the $10^{\text{th}}$, 2008 the Dagstuhl Seminar 08371 ``Fault-Tolerant Distributed Algorithms on VLSI Chips " was held in Schloss Dagstuhl~--~Leibniz Center for Informatics.
Dolev, Shlomi, Ebergen, Jo, Charron-Bost, Bernadette, Schmid, Ulrich   +3 more
core   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Cyclic Distributed Garbage Collection with Group Merger [PDF]

, 1997
This paper presents a new algorithm for distributed garbage collection and outlines its implementation within the Network Objects system. It supersedes the earlier version, /pubs/1997/548. The algorithm is based on a reference listing scheme augmented by
Helena Rodrigues, Jones, Richard E., Rodrigues, Helena, Rodrigues, Helena C.C.D., Jones, Richard, Richard Jones   +5 more
core   +1 more source

Distributed Routing and Channel Selection for Multi-Channel Wireless Sensor Networks

Journal of Sensor and Actuator Networks, 2017
We propose a joint channel selection and quality aware routing scheme for multi-channel wireless sensor networks that apply asynchronous duty cycling to conserve energy, which is common in many environmental monitoring applications.
Amitangshu Pal, Asis Nasipuri
doaj   +1 more source

Dynamic Ring Exploration with (H,S) View

Algorithms, 2020
The researches about a mobile entity (called agent) on dynamic networks have attracted a lot of attention in recent years. Exploration which requires an agent to visit all the nodes in the network is one of the most fundamental problems.
Tsuyoshi Gotoh, Yuichi Sudo, Fukuhito Ooshita, Toshimitsu Masuzawa   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Parameterisation of Algorithms for Distributed Constraint Optimisation via Potential Games

, 2008
This paper introduces a parameterisation of learning algorithms for distributed constraint optimisation problems (DCOPs). This parameterisation encompasses many algorithms developed in both the computer science and game theory literatures. It is built on
Jennings, N.R, Chapman, Archie, Rogers, Alex   +2 more
core   +1 more source

Path Planning for Multi-UAV Formation Rendezvous Based on Distributed Cooperative Particle Swarm Optimization

Applied Sciences, 2019
This paper studies the problem of generating cooperative feasible paths for formation rendezvous of unmanned aerial vehicles (UAVs). Cooperative path-planning for multi-UAV formation rendezvous is mostly a complicated multi-objective optimization problem
Zhuang Shao, Fei Yan, Zhou Zhou, Xiaoping Zhu   +3 more
doaj   +1 more source