Results 71 to 80 of about 308,840 (315)
Algorithms, 2009 In this work we focus on the energy efficiency challenge in wireless sensor networks, from both an on-line perspective (related to routing), as well as a network design perspective (related to tracking).
Paul G. Spirakis, Sotiris Nikoletseas
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Distributed data mining in grid computing environments [PDF]
, 2007 The official published version of this article can be found at the link below.The computing-intensive data mining for inherently Internet-wide distributed data, referred to as Distributed Data Mining (DDM), calls for the support of a powerful Grid with ...
Luo, P +7 more
core +1 more source
IEEE Access, 2021 This paper investigates the distributed fault detection problem for linear discrete time-varying heterogeneous multi-agent systems under relative output information.
Peilu Zou, Ping Wang, Chengpu Yu
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A Framework for Distributed Evolutionary Algorithms [PDF]
, 2002 This paper describes the recently released DREAM (Distributed Resource Evolutionary Algorithm Machine) framework for the automatic distribution of evolutionary algorithm (EA) processing through a virtual machine built from large numbers of individual machines linked by standard Internet protocols.
Maribel García Arenas +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Parallelizing RRT on distributed-memory architectures [PDF]
, 2011 This paper addresses the problem of improving the performance of the Rapidly-exploring Random Tree (RRT) algorithm by parallelizing it. For scalability reasons we do so on a distributed-memory architecture, using the message-passing paradigm.
Devaurs, Didier +5 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
IET BlockchainBlockchain is considered to be a promising technology due to its decentralization, open, and non tamperation. Nevertheless, the current blockchain system cannot replace traditional financial institutions because its performance and security indicators in
Linqing Xiao +3 more
doaj +1 more source