Results 61 to 70 of about 308,840 (315)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

SMT-based approaches to Model Checking of Distributed Broadcast Algorithms [PDF]

open access: yes, 2015
The validation of distributed algorithms is a crucial, although challenging, task. The processes executing these algorithms communicate to one another, their actions depend on the messages received, and their number is arbitrary.
S. Ghilardi   +3 more
core  

The distributed breakout algorithms

open access: yesArtificial Intelligence, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Katsutoshi Hirayama, Makoto Yokoo
openaire   +1 more source

Composition Algorithms for Conditional Distributions

open access: yes, 2022
This chapter is about two recently published algorithms that can be used to sample from conditional distributions. We show how the efficiency of the algorithms can be improved when a sample is required from many conditional distributions. Using real-data examples from educational measurement, we show how the algorithms can be used to sample from ...
Maarten Marsman   +2 more
openaire   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Performance Guarantees for Distributed Reachability Queries [PDF]

open access: yes, 2012
In the real world a graph is often fragmented and distributed across different sites. This highlights the need for evaluating queries on distributed graphs.
Wang, Xin   +2 more
core  

Distributed Asymptotic Minimization of Sequences of Convex Functions by a Broadcast Adaptive Subgradient Method [PDF]

open access: yes, 2011
We propose a non-hierarchical decentralized algorithm for the asymptotic minimization of possibly time-varying convex functions. In our method, each agent in a network has a private, local (possibly time-varying) cost function, and the objective is to ...
Renato L. G. Cavalcante   +11 more
core   +1 more source

List Defective Colorings: Distributed Algorithms and Applications [PDF]

open access: yes, 2023
The distributed coloring problem is at the core of the area of distributed graph algorithms and it is a problem that has seen tremendous progress over the last few years.
Kuhn, Fabian, Fuchs, Marc
core   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Birrell's Distributed Reference Listing Revisited [PDF]

open access: yes, 2005
The Java RMI collector is arguably the most widely used distributed garbage collector. Its distributed reference listing algorithm was introduced by Birrell in the context of Network Objects, where the description was informal and heavily biased toward ...
Dickman, Peter   +9 more
core   +1 more source

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