Results 101 to 110 of about 1,610,469 (333)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Video Analytics in Elite Soccer: A Distributed Computing Perspective. [PDF]

open access: yesProc IEEE Sens Array Multichannel Signal Process Workshop, 2022
Jha D   +6 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Detecting Arbitrary Attacks Using Continuous Secured Side Information in Wireless Networks

open access: yesIEEE Access, 2017
This paper focuses on Byzantine attack detection for Gaussian two-hop one-way relay network, where an amplify-and-forward relay may conduct Byzantine attacks by forwarding altered symbols to the destination.
Ruohan Cao
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Deep distributed computing to reconstruct extremely large lineage trees. [PDF]

open access: yesNat Biotechnol, 2022
Konno N   +11 more
europepmc   +1 more source

Computing for Perturbative QCD - A Snowmass White Paper

open access: yes, 2013
We present a study on high-performance computing and large-scale distributed computing for perturbative QCD calculations.Comment: 21 pages, 5 ...
,   +29 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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