Results 61 to 70 of about 2,116,890 (336)

Mars Climate Database version 5 [PDF]

, 2012
The Mars Climate Database (MCD) is a database of meteorological fields derived from General Circulation Model (GCM) numerical simulations [2,4] of the Martian atmosphere and validated using available observational data.
Chauffray, J.-Y., Colaitis, A., Desjean, M.-C., Forget, F., Gonzalez-Galindo, F., Huot, J.-P., Lefevre, F., Lewis, S. R., Lopez-Valverde, M. A., Madeleine, J.-B., Millour, E., Montabone, L., Montmessin, F., Navarro, T., Read, P. L., Spiga, A.   +15 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

ART and ARTMAP Neural Networks for Applications: Self-Organizing Learning, Recognition, and Prediction [PDF]

, 1996
ART and ARTMAP neural networks for adaptive recognition and prediction have been applied to a variety of problems. Applications include parts design retrieval at the Boeing Company, automatic mapping from remote sensing satellite measurements, medical ...
Carpenter, Gail A., Gjaja, Marin N., Gopal, Sucharita, Markuzon, Natalya, Woodcock, Curtis E.   +4 more
core   +1 more source

Database Consistency Using Update-Ordering in Distributed Databases

Journal of Algorithms & Computational Technology, 2007
Database consistency is one of the major issues in replicated database in distributed database systems. The logical design for the replicated nodes and the transaction management mechanism are two aspects that give a serious impact to the performance and
W. N. Shuhadah, M. Mat Deris, A. Noraziah, M.Y. Saman, M. Rabiei   +4 more
doaj   +1 more source

Distributed Database Systems in the Dynamic Networks Environment

Communications, 2011
This article describes a new architecture of a distributed database system, which is designed especially for the dynamic networks environment. Problems with the architecture of a traditional distributed database system are explained, and a solution is ...
Jan Janech, Tomas Baca
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Operator parallel optimization strategy for distributed databases

Xibei Gongye Daxue Xuebao
With the continuous development of network technology, the scale of data has shown explosive growth, which leads gradually to replacing traditional single machine databases with distributed databases.
LIU Wenjie, LYU Jingchao
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Component Approach to Software Development for Distributed Multi-Database System [PDF]

The paper deals with a component based approach for software development in a distributed environment for the database retrieval operations. A Core Component for a distributed multi-database system has been proposed.
Muthaiyan MADIAJAGAN, Sri Hari Haran SEENIVASAN, Vijayakumar BALAKRISHNAN   +2 more
core