Results 101 to 110 of about 5,179,593 (338)
, 2014 We present a heuristic derivation of Gaussian approximations for stochastic chemical reaction systems with distributed delay. In particular we derive the corresponding chemical Langevin equation.
Benson S. W. +6 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Delay-Dependent Stability Criterion of Caputo Fractional Neural Networks with Distributed Delay
Discrete Dynamics in Nature and Society, 2014 This paper is concerned with the finite-time stability of Caputo fractional neural networks with distributed delay. The factors of such systems including Caputo’s fractional derivative and distributed delay are taken into account synchronously.
Abdulaziz Alofi +3 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Distributed delays stabilize negative feedback loops [PDF]
, 2009 Linear scalar differential equations with distributed delays appear in the study of the local stability of nonlinear differential equations with feedback, which are common in biology and physics. Negative feedback loops tend to promote oscillation around
Bernard, Samuel
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Computation, 2019 In this paper, we propose and investigate a diffusive viral infection model with distributed delays and cytotoxic T lymphocyte (CTL) immune response.
Khalid Hattaf
doaj +1 more source
Investigation of the complex dynamics and regime control in Pierce diode with the delay feedback
, 2005 In this paper the dynamics of Pierce diode with overcritical current under the influence of delay feedback is investigated. The system without feedback demonstrates complex behaviour including chaotic regimes.
A. E. Hramov +10 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Electronic Journal of Differential Equations, 2003 We apply the results of our previous paper "Oscillation of equations with positive and negative coefficients and distributed delay I: General results" to the study of oscillation properties of equations with several delays and positive and negative ...
Leonid Berezansky, Elena Braverman
doaj