Results 91 to 100 of about 273,919 (256)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Cascaded estimation of tire forces for articulated mining vehicles based on sliding mode observers
Meitan kexue jishuSpecialized vehicles in mining often use heavy-duty solid rubber tires or polyurethane-filled tires, which exhibit significantly different tire-road contact mechanisms and operating environments compared to traditional road vehicles.
Zhongbin WU +5 more
doaj +1 more source
Dynamic-boundary-based lateral motion synergistic control of distributed drive autonomous vehicle. [PDF]
Sci Rep, 2021 Wang K, Ding W, Yang M, Zhu Q.
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Research on Decoupling Control of Four-Wheel Steering Distributed Drive Electric Vehicles
World Electric Vehicle JournalTo address the issue of limited accuracy in vehicle lateral and longitudinal dynamics control—caused by the strong coupling and nonlinearity between the four-wheel steering and distributed drive systems, particularly under crosswind disturbances—a ...
Jie Zhu, Chengye Liu
doaj +1 more source
On the distribution of individual daily driving distances
Transportation Research Part B: Methodological, 2017 Plug-in electric vehicles (PEV) can reduce greenhouse gas emissions. However, the utility of PEVs, as well as reduction of emissions is highly dependent on daily vehicle kilometres travelled (VKT). Further, the daily VKT by individual passenger cars vary strongly between days.
Plötz, Patrick +2 more
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source