Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Student leadership development: A functional framework [PDF]
This article presents a longitudinal, qualitative case study of a student leadership program in a Catholic secondary school in Perth, Western Australia.
Hine, Gregory S.C.
core +3 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Distributed leadership has been shown to improve teacher job satisfaction and reduce teacher job stress. However, few studies have thoroughly explored the indirect effects of distributed leadership on increasing the teachers’ burden in school ...
Jian Li, Eryong Xue, Yuxuan Liu
doaj +1 more source
The Co-principalship: an Alternative to the Traditional Principalship [PDF]
According to Spillane (2006), distributed leadership occurs when leadership functions are shared by a number of people in an organization or team with leadership emerging from the interactions within the group.
Eckman, Ellen, Kelber, Sheryl Talcott
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Hey, this school library isn't what it used to be: The change process and the sociopolitical realities of implementing a curricularly integrated information literacy program [PDF]
This study sought to add to the knowledge and understanding of the organizational change process for successfully implementing an integrated information literacy program in one American high school.
Rojtas-Milliner, Mary Cay
core +1 more source
Blockchain, Leadership And Management: Business AS Usual Or Radical Disruption? [PDF]
The Internet provided the world with interconnection. However, it did not provide it with trust. Trust is lacking everywhere in our society and is the reason for the existence of powerful intermediaries aggregating power.
Chartier-Rueg, T. C. (Theodore) +1 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A role-based perspective on leadership as a network of relationships.
The research described in this article seeks to address the question of the extent to which a role-based perspective can provide insight into the distributed and networked form of ...
Kakabadse, Andrew P., Sheard, A. G.
core +1 more source

