Results 121 to 130 of about 3,609,462 (370)

Focusing the kaleidoscope: Investigating the newly formed role of “Academic Lead” at a research-led University [PDF]

open access: yes, 2012
This paper reports on a Leadership Foundation funded research project exploring the ways in which one UK institution has implemented a new ‘distributed’ leadership model.
Floyd, Alan, Fung, Dilly
core  

Leadership in Improving Schools: A Qualitative Perspective [PDF]

open access: yes, 2008
This article reports early case-study data gathered from 20 schools involved in the ‘Impact of School Leadership on Pupil Outcomes’ project. We present and discuss the perceptions of headteachers and other school leaders regarding leadership factors that
Alison Kington   +21 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Att närvara där det händer – det pedagogiska ledarskapets betydelse för att leda lärares återkopplingsarbete

open access: yesNordic Studies in Education
This article discusses instructional leadership and its implications for professional development of formative assessment conducted by teachers. Theories of instructional leadership claim that distributed leadership is seen as a strategy for principals ...
Anna Sarri Krantz
doaj   +1 more source

Authority, Power and Distributed Leadership [PDF]

open access: yes, 2016
This is the Accepted Manuscript version of an article accepted for publication in Management and Education following peer review. The version of record, Philip Woods, ‘Authority, power and distributed leadership’, Management and Education, Vol 30(4): 155-
Blackmore J   +10 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Distributed Digital Leadership in Grundschulen

open access: yesMedienimpulse
Die vorliegende Delphi-Studie untersucht zentrale Handlungsstrategien für digitale Schulentwicklungsprozesse in Grundschulen unter der theoretischen Perspektive des Distributed Digital Leadership (DDL).
Nina Autenrieth
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Building an Aging Advocacy Network: Findings from the New Hampshire Senior Leadership Series [PDF]

open access: yes, 2015
Public policy related to senior issues has not kept pace with the changes called for by an aging population. Advocacy is an important part of the policy landscape as it promotes a united effort to create change and encourage legislative action. Effective
Davie, Laura K.   +2 more
core   +1 more source

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