Results 61 to 70 of about 633,827 (270)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

RESEARCH OF PARAMETERS OF ENCODING OF THE ALGORITHM WITH VARIABLE FRAGMENTATION OF THE UNIT

Системный анализ и прикладная информатика, 2018
This article presents recommendations on the selection of parameters of the encryption algorithm with variable fragmentation of the block, developed on the basis of a study of the obtained results of the algorithm with different encryption parameters (p ...
K. O. Zakharova
doaj   +1 more source

Cycle type of random permutations: a toolkit

Discrete Analysis, 2022
Cycle type of random permutations: a toolkit, Discrete Analysis 2022:9, 36 pp. What does a random permutation look like? This general question has led to a great deal of research, and this article provides a convenient single reference for many results,
Kevin Ford
doaj   +1 more source

Prime number patterns [PDF]

, 2008
This dissertation focuses on studying the patterns in the prime number distribution. It visualizes the distribution of prime numbers in a graphic manner through the usage of the Microsoft Excel software.
Koh, Kristal , Mel Ling
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Challenges faced in the conservation of rare antelope: a case study on the northern basalt plains of the Kruger National Park

Koedoe: African Protected Area Conservation and Science, 2002
The conservation of rare antelope has long been one of the goals of the Kruger National Park. The roan antelope Hippotragus equinus, and to a lesser extent the tsessebe Damaliscus lunatus, represent low-density species or rare antelope in the park ...
C.C. Grant, T. Davidson, P.J. Funston, D.J. Pienaar   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Distribution of Prime Numbers Fundamental Theorem [PDF]

Bulletin of Mathematical Sciences and Applications, 2013
In 1849, the German mathematician Gauss large average distribution density of primesnear x. Based on the density of the Gauss proposed regional distribution of prime numbers theorem.And regional distribution of prime numbers theorem proved easy to understand way. Thefundamental theorem to obtain the distribution of prime numbers.
openaire   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source