Results 41 to 50 of about 14,157 (261)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Еstimation of randomity of generators of keys of the crypto system
Қарағанды университетінің хабаршысы. Математика сериясы, 2018 The aim of the study is to develop an algorithm for constructing an integer random variable representing random components of the keys of the RSA cryptosystem, and determining the table for the distribution of its probabilities.
M.T. Jenaliyev, А.Т. Nurtazin
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
On properties of the numbers coprime with the primes up to p_n
Le Matematiche, 2006 In this paper we investigate about the effective distribution of the numbers coprime with the primes up to p_n . More precisely we prove that these numbers form a periodically monotone sequence . Then we examine some properties of this sequence which, in
Giovanni Fiorito
doaj
On the irregularity of the distribution of the sums of pairs of odd primes
International Journal of Mathematics and Mathematical Sciences, 2002 Let P2(n) denote the number of ways of writing n as a sum of two odd primes. We support a conjecture of Hardy and Littlewood concerning P2(n) by showing that it holds in a certain average sense. Thereby showing the irregularity of P2(n).
George Giordano
doaj +1 more source
Predicting Maximal Gaps in Sets of Primes
Mathematics, 2019 Let q > r ≥ 1 be coprime integers. Let P c = P c ( q , r , H ) be an increasing sequence of primes p satisfying two conditions: (i) p ≡ r (mod q) and (ii) p starts a prime k-tuple with a given pattern H ...
Alexei Kourbatov, Marek Wolf
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On the distribution of Hawkins’ random “primes” [PDF]
Journal de théorie des nombres de Bordeaux, 2009 Hawkins introduced a probabilistic version of Erathosthenes’ sieve and studied the associated sequence of random “primes” (p k ) k≥1 . Using various probabilistic techniques, many authors have obtained sharp results concerning these random “primes”, which are often in agreement with certain classical theorems or conjectures for prime numbers.
openaire +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source