Results 81 to 90 of about 166,083,503 (302)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

β-Aminobutyric Acid (BABA)-Induced Resistance in Arabidopsis thaliana: Link with Iron Homeostasis

open access: yesMolecular Plant-Microbe Interactions, 2014
β-Aminobutyric acid (BABA) is a nonprotein amino acid inducing resistance in many different plant species against a wide range of abiotic and biotic stresses. Nevertheless, how BABA primes plant natural defense reactions remains poorly understood.
Emmanuel Koen   +11 more
doaj   +1 more source

Evasiveness and the Distribution of Prime Numbers

open access: yesCoRR, 2010
12 pages (conference version for STACS 2010)
László Babai   +3 more
openaire   +5 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Different Approaches to the Distribution of Primes [PDF]

open access: yesMilan Journal of Mathematics, 2010
The author gives both a survey of the classic history, for the study of prime numbers, and a glimpse into a very recent approach to the distribution of primes, namely, a more elementary study based on the concept of ``pretentiousness'', among multiplicative functions (namely, functions \(f\) such that \(f(mn)=f(m)f(n)\), for all coprime natural numbers
openaire   +1 more source

Distribution of Square-Prime Numbers

open access: yesMissouri Journal of Mathematical Sciences, 2022
For $a \neq 1$ and $p$ prime, we define numbers of the form $pa^2$ to be Square-Prime (SP) Numbers. For example, 75 = 3 $\cdot$ 25; 108 = 3 $\cdot$ 36; 45 = 5 $\cdot$ 9. These numbers are listed in the OEIS as A228056. We study the properties of these numbers, their distribution/density and also develop a few claims on their distribution/density.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Distribution of primes

open access: yes, 2016
Knowledge about number theory and prime numbersEuclid proved that the number of prime numbers is infinite. Prime numbers seem to be arranged in an unpredictable way, but sometimes patterns emerge.
Zenil, Hector
core   +2 more sources

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