Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Allocation of logistic risk-investment in public-private-partnership – use of fuzzy TOPSIS method
MATEC Web of Conferences, 2018 Appropriate risk assessment related to the project, and then its distribution between partners is the core of cooperation in the framework of public-private partnership (PPP).
Kauf Sabina, Tłuczak Agnieszka
doaj +1 more source
Municipal distribution of ovarian cancer mortality in Spain
BMC Cancer, 2008 Background Spain was the country that registered the greatest increases in ovarian cancer mortality in Europe. This study describes the municipal distribution of ovarian cancer mortality in Spain using spatial models for small-area analysis.
Vidal Enrique +9 more
doaj +1 more source
A Comprehensive Contamination Investigation of Bohai Bay Seawater: Antibiotics Occurrence, Distribution, Ecological Risks and Their Interactive Factors. [PDF]
Int J Environ Res Public Health, 2023 Tian L +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Critically raw materials as potential emerging environmental contaminants, their distribution patterns, risks and behaviour in floodplain soils contaminated by heavy metals. [PDF]
Sci Rep, 2023 Kanianska R +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Spatial Distribution, Potential Risks and Source Identification of Heavy Metals in the Coastal Sediments of the Northern Beibu Gulf, South China Sea. [PDF]
Int J Environ Res Public Health, 2022 Yang C, Wang L, Liu Y, Shan B, Sun D.
europepmc +1 more source
Detection, Distribution and Health Risk Assessment of Toxic Heavy Metals/Metalloids, Arsenic, Cadmium, and Lead in Goat Carcasses Processed for Human Consumption in South-Eastern Nigeria [PDF]
, 2021 Emmanuel Okechukwu Njoga +6 more
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source