Results 91 to 100 of about 642,937 (309)

The spatial and temporal distribution of risks associated with low level radioactive waste disposal.

open access: yes, 1988
The disposal of waste is a growing environmental, political, and economic problem. Low level radioactive waste (LLW) disposal is no exception. The major purposes of this dissertation are to examine the economic tradeoffs which arise in the process of LLW
Thompson, Philip Blinn.
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Collective investments, distribution of risks

open access: yes, 2007
Katedra obchodního právaDepartment of Business LawFaculty of LawPrávnická ...
Kavková, Kateřina
core  

Distribution of risks of change in the price of a foreign trade contract

open access: yes, 2020
В связи с вступлением России во Всемирную торговую организацию в новых условиях, в рамках правовой системы ВТО происходит существенное расширение и активизация внешнеэкономических отношений. В целях эффективного учета федеральных и региональных интересов
Bakueva, M. G., Бакуева, М. Г.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Towards a Topological Representation of Risks and Their Measures

open access: yesRisks, 2018
In risk theory, risks are often modeled by risk measures which allow quantifying the risks and estimating their possible outcomes. Risk measures rely on measure theory, where the risks are assumed to be random variables with some distribution function ...
Tomer Shushi
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Spatiotemporal distribution of ecological risk of antibiotics in seven major river basins of China: An optimized multilevel assessment approach

open access: yesWater Science and Technology
Antibiotics have been recognized as emerging pollutants due to their ecological and human health risks. This paper aims to enhance the ecological risk assessment (ERA) framework for antibiotics, to illustrate the distribution of these risks across ...
Wei Liu   +4 more
doaj   +1 more source

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