Results 101 to 110 of about 642,937 (309)

Identification and ranking of supply chain risks in Digital Libraries State universities of Tehran based on ISO 31000 standard.

open access: yesIranian Journal of Information Processing & Management, 2022
The present research has been done with a view to identifying and ranking the supply chain risks in digital libraries of state universities in Tehran based on the 2018 version of ISO 31000.
Mitra Samiei   +2 more
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The risk ethics of autonomous vehicles: a continuous trolley problem in regular road traffic [PDF]

open access: yes, 2022
Is the ethics of autonomous vehicles (AVs) restricted to weighing lives in unavoidable accidents? We argue that AVs distribute risks between road users in regular traffic situations, either explicitly or implicitly.
Uhl, Matthias, Krügel, Sebastian
core  

Ruin Probability Analysis in Automobile Insurance Using Gamma-Cubic Transmuted Exponential Distribution for Claim Severity [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences
Insurance companies must confront and manage financial risks to ensure their survival. This article analyzes and manages risks by estimating ruin probability using the newly developed Gamma-Cubic Transmuted Exponential (GCTE) claim severity distribution.
Jiramet Hengcharoensuk, Adisak Moumeesri
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Direct and Hierarchical Models for Aggregating Spatially Dependent Catastrophe Risks

open access: yesRisks, 2019
We present several fast algorithms for computing the distribution of a sum of spatially dependent, discrete random variables to aggregate catastrophe risk. The algorithms are based on direct and hierarchical copula trees.
Rafał Wójcik   +2 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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