Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Pendekatan psikologi dakwah menangani histeria remaja muslim di Selangor [PDF]
, 2015 Gejala histeria dalam kalangan remaja di Malaysia merupakan epidemik sosial yang telah lama berlaku dalam masyarakat. Kejadian tersebut mengganggu proses pengajaran dan pembelajaran, psikologi, jasmani dan spiritual remaja.
Saparudin, Intan Farhana
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Research on additional damping control strategy of flexible distribution transformer
Frontiers in Energy ResearchDisturbances to the power system may lead to relative swing between synchronous generator rotors, causing low-frequency oscillation problems in the absence of damping.
Guowei Guo +7 more
doaj +1 more source
Automatic load sharing of distribution transformer for overload protection. [PDF]
BMC Res Notes, 2020 Nebey AH.
europepmc +1 more source
Studi Analisa Pengaruh Pembebanan dan Temperatur Lingkungan terhadap Susut Umur Tranformator Daya pada Gardu Induk Garuda Sakti [PDF]
, 2016 Power transformers is an essential equipment in the distribution of electricity to a substation, thus cultivated a power transformer to function in accordance with its design lifespan.
', F. (Firdaus), ', K. (Kurniawan)
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Distribution Transformer Parameters Detection Based on Low-Frequency Noise, Machine Learning Methods, and Evolutionary Algorithm. [PDF]
Sensors (Basel), 2020 Jancarczyk D, Bernaś M, Boczar T.
europepmc +1 more source
, 2011 Transformers play an important role in providing a reliable and efficient electricity supply and are one of the most critical equipments in electric power transmission and distribution systems.
Chen, G, Hao, J, Liao, R
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