Results 111 to 120 of about 250,902 (302)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A DETERMINATION OF THE FLUX DENSITY IN CORE OF DISTRIBUTION TRANSFORMERS, WHAT BUILT WITH THE COMMON USING OF GRAIN AND NON GRAIN ORIENTED MAGNETIC STEELS

open access: yesElectrical engineering & Electromechanics, 2015
Purpose. The development of calculation method to determinate the flux densities in different parts of the magnetic cores of distribution transformers, what built from different types magnetic steel (mixed core). Methodology.
I.V. Pentegov   +3 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

SIMULASI PENGEMBANGAN TRAFO DISTRIBUSI BERDASARKAN PERTUMBUHAN BEBAN MENGGUNAKAN MODEL DKL 3,2 DAN SOFTWARE ETAP 7.0.0 TAHUN 2012 – 2016 DI UPJ BATANG [PDF]

open access: yes, 2012
Electric energy infrastructure as one of the livelihood of the people concerning the distribution of electrical energy must be able to guarantee in an amount sufficient, reasonable price and good quality.
Mahardika, Dhimas   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Differentiated Governance Strategies for Distribution Transformer Overload and Three-Phase Imbalance Considering Source-Load Regulation

open access: yesZhongguo dianli
Aiming at the mixed problems of three-phase imbalance and heavy overload of distribution transformers caused by large-scale access of single-phase distributed photovoltaic and single-phase charging piles, a differentiated governance strategy for heavy ...
Qiang YANG   +7 more
doaj   +1 more source

Abstract Hidden Markov Models: a monadic account of quantitative information flow

open access: yes, 2019
Hidden Markov Models, HMM's, are mathematical models of Markov processes with state that is hidden, but from which information can leak. They are typically represented as 3-way joint-probability distributions.
McIver, Annabelle   +2 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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