Results 81 to 90 of about 6,467 (228)

Distributionally robust optimization of a Canadian healthcare supply chain to enhance resilience during the COVID-19 pandemic. [PDF]

Comput Ind Eng, 2022
Ash C, Diallo C, Venkatadri U, VanBerkel P.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Distributionally Robust Optimization Adaptive Event‐Triggered SMPC for DC‐DC Converters Subject to Unknown Disturbances and DoS Attacks

IET Power Electronics
In this paper, we present adaptive event‐triggered distributionally robust optimization stochastic model predictive control (AET‐DROSMPC) applied to DC‐DC converters subject to unknown disturbances and denial of service (DoS) attacks.
Yadong Chen, Peng Cheng
doaj   +1 more source

A Distributionally Robust Optimization Method for Passenger Flow Control Strategy and Train Scheduling on an Urban Rail Transit Line. [PDF]

Engineering (Beijing), 2022
Lu Y, Yang L, Yang K, Gao Z, Zhou H, Meng F, Qi J.   +6 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Carbon-aware mobile energy storage system scheduling in active power distribution systems under PV and traffic uncertainties

Energy Reports
Carbon emission flow (CEF) is a promising approach for assessing both generation-and consumption-side carbon footprints in the power system sector. In this study, we propose a carbon-aware mobile energy storage system (MESS) scheduling framework that ...
Panggah Prabawa, Dae-Hyun Choi
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Distributionally Robust Bayesian Optimization via Sinkhorn-Based Wasserstein Barycenter

Machine Learning and Knowledge Extraction
This paper introduces a novel framework for Distributionally Robust Bayesian Optimization (DRBO) with continuous context that integrates optimal transport theory and entropic regularization.
Iman Seyedi, Antonio Candelieri, Francesco Archetti   +2 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Energy Management of PV-Enabled Battery Charging Swapping Stations for Electric Vehicles in Active Distribution Systems Under Uncertainty

Energies
In this paper, we propose a data-driven distributionally robust optimization (DRO) framework that ensures the economical and robust operation of solar photovoltaic (PV)-integrated battery charging swapping stations (BCSSs) for electric vehicles (EVs ...
Haram Kim, Sangyoon Lee, Dae-Hyun Choi
doaj   +1 more source