Results 121 to 130 of about 33,178 (299)
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Научно-технический вестник информационных технологий, механики и оптикиIn the paper, the problem of compensation of external disturbance in multichannel systems with unmeasurable state vector and delay in the control channel is considered. It is assumed that the disturbance has a harmonic form.
V. H. Bui, V. A. Zhdanov, A. A. Margun
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Geometric Disturbance Observer Based Control for Multirotors
In this paper we propose a disturbance observer based control for the class of multirotor aerial vehicles having co-planar and collinear propellers, following a geometric approach. The control scheme is based on the well known inner-outer loop structure,
Monteriu' A. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Adaptive Second-Order Fixed-Time Sliding Mode Controller with a Disturbance Observer for Electronic Throttle Valves. [PDF]
Sensors (Basel), 2023 Feng Y, Long Y, Yao C, Song E.
europepmc +1 more source
H∞ Disturbance Observer Design
, 2010 干擾觀測器可以達成即時線上觀測對系統的未知干擾。早期的干擾觀測器只能針對某些種類的干擾進行估測，在此篇論文中提出了一個新的頻域塑形觀測器。此種頻域塑形觀測器展現了一個類比的設計方法相對於回授控制系統的控制器設計。藉由此種類比設計方法的優勢，我們能夠藉由H∞的控制器設計技巧，來達成此種頻域塑形觀測器的系統化設計。此種觀測器建立在頻域設計上，不只考慮了估測的能力，同時兼顧了系統的不確定性與雜訊對系統的敏感度的影響，並且可以用來估測大部分的干擾。如果將此種觀測器運用在干擾抑制控制上的話 ...
陳祈澈, Chen, Chi-Che
core