Results 1 to 10 of about 1,312,330 (378)
In Silico Modeling of Myelin Oligodendrocyte Glycoprotein Disulfide Bond Reduction by Phosphine-Borane Complexes. [PDF]
Pharmaceuticals (Basel)Background: Neurodegenerative diseases can cause vision loss by damaging retinal ganglion cells in the optic nerve. Novel phosphine-borane compounds (PBs) can protect these cells from oxidative stress via the reduction of disulfide bonds.
Remtulla R, Das SK, Levin LA.
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Production and characterization of neurosecretory protein GM using Escherichia coli and Chinese Hamster Ovary cells [PDF]
FEBS Open Bio, 2015 Neurosecretory protein GL (NPGL) and neurosecretory protein GM (NPGM) are paralogs recently discovered in birds and in mammals. The post‐translational products of NPGL and of NPGM genes include a signal peptide sequence, a glycine amidation signal, and a
Keiko Masuda +4 more
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Validation of the Intermolecular Disulfide Bond in Caspase-2. [PDF]
Biology (Basel)Caspases are a family of proteins involved in cell death. Although several caspase members have been well characterized, caspase-2 remains enigmatic. Caspase-2 has been implicated in several phenotypes, but there has been no consensus in the field about ...
Amason ME +4 more
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Stability and functional consequences of disulfide bond engineering in Aspergillus flavus uricase. [PDF]
Sci RepDisulfide bond engineering is a promising strategy for enhancing the stability and functional lifespan of enzymes in therapeutic and industrial applications.
Rahbar MR +6 more
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Research Progress of Disulfide Bond Based Tumor Microenvironment Targeted Drug Delivery System. [PDF]
Int J NanomedicineWeiran Ma,1,2 Xiaoying Wang,2 Dongqi Zhang,3 Xupeng Mu1 1Scientific Research Center, China-Japan Union Hospital of Jilin University, Changchun, 130033, People’s Republic of China; 2Jilin University School of Pharmaceutical Sciences, Changchun, 130021 ...
Ma W, Wang X, Zhang D, Mu X.
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Analysis of Disulfide Bond Formation [PDF]
Current Protocols in Protein Science, 2017 AbstractIn this unit, protocols are provided for detection of disulfide bond formation in cultures of intact cells and in an in vitro translation system containing isolated microsomes or semi‐permeabilized cells. First, the newly synthesized protein of interest is biosynthetically labeled with radioactive amino acids in a short pulse.
Braakman, Ineke +3 more
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Scientific Reports, 2021 Generally, intermolecular disulfide bond contribute to the conformational protein stability. To identify sites where intermolecular disulfide bond can be introduced into the Fab’s constant domain of the therapeutic IgG, Fab mutants were predicted using ...
Hitomi Nakamura +4 more
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Polarity of disulfide bonds [PDF]
Protein Science, 1993 1Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 ...
Gary J. Pielak +2 more
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Foods, 2023 Wheat, maize, cassava, mung bean and sweet potato starches have often been added to dough systems to improve their hardness. However, inconsistent effects of these starches on the dough quality have been reported, especially in refrigerated dough.
Yu Zhou +4 more
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The name's bond……disulfide bond [PDF]
Current Opinion in Structural Biology, 2007 A repeating theme in the structural biology of disulfide oxidants and isomerases is the extraordinary architectural similarity between functionally related proteins from prokaryotes and eukaryotes. The recently determined structure of full-length yeast protein disulfide isomerase (PDI) reveals a U-shaped molecule with two redox-active sites. It bears a
Heras, Begona +3 more
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