Results 21 to 30 of about 40,342 (186)

Disulfides from the Brown Alga Dictyopteris membranacea Suppress M1 Macrophage Activation by Inducing AKT and Suppressing MAPK/ERK Signaling Pathways

Marine Drugs, 2020
Inflammation is part of the organism’s response to deleterious stimuli, such as pathogens, damaged cells, or irritants. Macrophages orchestrate the inflammatory response obtaining different activation phenotypes broadly defined as M1 (pro-inflammatory ...
Maria G. Daskalaki, Paraskevi Bafiti, Stefanos Kikionis, Maria Laskou, Vassilios Roussis, Efstathia Ioannou, Sotirios C. Kampranis, Christos Tsatsanis   +7 more
doaj   +1 more source

Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER [PDF]

, 2017
Folding of proteins entering the secretory pathway in mammalian cells frequently requires the insertion of disulfide bonds. Disulfide insertion can result in covalent linkages found in the native structure as well as those that are not, so‐called non ...
Elias SJ Arnér, Fourie AM, Greg J Poet, Marcel Lith, Marie Anne Pringle, Neil J Bulleid, Ojore BV Oka, Philip J Robinson, Zhenbo Cao   +8 more
core   +2 more sources

Protein disulfide engineering

FEBS Letters, 2013
Improving the stability of proteins is an important goal in many biomedical and industrial applications. A logical approach is to emulate stabilizing molecular interactions found in nature. Disulfide bonds are covalent interactions that provide substantial stability to many proteins and conform to well‐defined geometric conformations, thus making them ...
Dombkowski, Alan A., Sultana, Kazi Zakia, Craig, Douglas B.   +2 more
openaire   +2 more sources

Computational investigation of the lubrication behaviors of dioxides and disulfides of molybdenum and tungsten in vacuum

Friction, 2017
Lamellar compounds such as the disulfides of molybdenum and tungsten are widely used as additives in lubricant oils or as solid lubricants in aerospace industries.
Jingyan Nian, Liwei Chen, Zhiguang Guo, Weimin Liu   +3 more
doaj   +1 more source

Preparation and flotation performance of thionocarbamates

工程科学学报, 2023
To address the problems of byproduct treatment and pollution in thionocarbamate preparation, four novel processes for preparing O-isopropyl-N-ethyl thionocarbamate (IPETC) were designed, which can coproduce 4-(tert-butyl)benzyl mercaptan (BBSH), sodium ...
Xin MA, Zhan-fang CAO, Shuai WANG, Xiao-ping HUANG, Hong ZHONG   +4 more
doaj   +1 more source

Novel strategies for the synthesis of unsymmetrical glycosyl disulfides [PDF]

, 2016
yesNovel strategies for the efficient synthesis of unsymmetrical glycosyl disulfides are reported. Glycosyl disulfides are increasingly important as glycomimetics and molecular probes in glycobiology. Sialosyl disulfides are synthesised directly from the
Adinolfi, Al-Saraireh, Andre, Aversa, Bailey, Bernardes, Bradley R. Springett, Brito, Caraballo, Caraballo, Davis, Falconer, Fernandez-Gonzalez, Ferrier, Gamblin, Goreti Ribeiro Morais, Grayson, Grayson, Hamachi, Harp, Hummel, Illyes, Kiefel, Knapp, Liang, Liang, Lisa Schröder, Macindoe, Mandal, Martin Pauze, Matthew Northrop, Murthy, Musiejuk, Pei, Pei, Ribeiro Morais, Ribeiro Morais, Ribeiro Morais, Robert A. Falconer, Stellenboom, Szilagyi   +40 more
core   +1 more source

Efficient preparation of unsymmetrical disulfides by nickel-catalyzed reductive coupling strategy

Nature Communications, 2022
The preparation of disulfides mainly relies on oxidative couplings of two sulfur-containing compounds, a strategy which has side reactions and other shortcomings.
Fei Wang, Ying Chen, Weidong Rao, Lutz Ackermann, Shun-Yi Wang   +4 more
doaj   +1 more source

Dynamic Thiol Disulphide Homeostasis In Patients Diagnosed With Acute Pulmonary Thromboembolism In Emergency Department

Ankara Medical Journal, 2021
INTRODUCTION: This study aims to investigate the dynamic thiol-disulfide balance in the early period of patients diagnosed with acute pulmonary thromboembolism in the emergency department.
Gül Pamukçu Günaydın, Fatih Tanrıverdi, SERKAN DEMİRCAN, FERHAT İÇME, Yavuz Otal, Yucel Yuzbasioglu, erdem haytaç, Pervin Baran, Cemile Bicer   +8 more
doaj   +1 more source

Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation [PDF]

, 2017
The relationship between protein synthesis, folding and disulfide formation within the endoplasmic reticulum (ER) is poorly understood. Previous studies have suggested pre-existing disulfide links are absolutely required to allow protein folding and ...
Bulleid, Neil J., Pringle, Marie Anne, Robinson, Philip J., Woolhead, Cheryl A.   +3 more
core   +1 more source

Protein disulfide-isomerase interacts with a substrate protein at all stages along its folding pathway [PDF]

, 2014
In contrast to molecular chaperones that couple protein folding to ATP hydrolysis, protein disulfide-isomerase (PDI) catalyzes protein folding coupled to formation of disulfide bonds (oxidative folding).
A Jansens, A Land, A Pirneskoski, A. Katrine Wallis, Alistair G. Irvine, AR Karala, AR Karala, AY Denisov, B van den Berg, B van den Berg, B van den Berg, CB Anfinsen, Claudia A. Blindauer, CPM van Mierlo, CPM van Mierlo, CW Gruber, DP Goldenberg, E van Anken, F Hatahet, G Kozlov, G Wagner, HC Shin, HC Shin, J Riemer, JH Laity, JL Arolas, JS Weissman, JS Weissman, L Wang, LJ Byrne, Lloyd W. Ruddock, M Narayan, Mark J. Howard, Michelle L. Rowe, Narinder Sanghera, NJ Bulleid, NJ Darby, P Klappa, P Venetianer, RA Williamson, RB Freedman, RF Goldberger, Richard A. Williamson, RJ Ellis, Robert B. Freedman, S Masui, S Talluri, Salvador Ventura, TE Creighton, TE Creighton, TE Creighton, TE Creighton, VD Nguyen, VD Nguyen, WF Vranken   +54 more
core   +3 more sources