Results 21 to 30 of about 54,679 (294)

Metal-free photo-induced sulfidation of aryl iodide and other chalcogenation

open access: yesFrontiers in Chemistry, 2022
A photo-induced C-S radical cross-coupling of aryl iodides and disulfides under transition-metal and external photosensitizer free conditions for the synthesis of aryl sulfides at room temperature has been presented, which features mild reaction ...
Shuai Mao   +12 more
doaj   +1 more source

Tuning the Solubility of Self-Assembled Fluorescent Aromatic Cages Using Functionalized Amino Acid Building Blocks

open access: yesFrontiers in Chemistry, 2019
We previously reported novel fluorescent aromatic cages that are self-produced using a set of orthogonal dynamic covalent reactions, operating simultaneously in one-pot, to assemble up to 10 components through 12 reactions into a single cage-type ...
Marcin Konopka   +6 more
doaj   +1 more source

Efficient preparation of unsymmetrical disulfides by nickel-catalyzed reductive coupling strategy

open access: yesNature Communications, 2022
The preparation of disulfides mainly relies on oxidative couplings of two sulfur-containing compounds, a strategy which has side reactions and other shortcomings.
Fei Wang   +4 more
doaj   +1 more source

Thiol Metabolism and Volatile Metabolome of Clostridioides difficile

open access: yesFrontiers in Microbiology, 2022
Clostridioides difficile (previously Clostridium difficile) causes life-threatening gut infections. The central metabolism of the bacterium is strongly influencing toxin production and consequently the infection progress. In this context, the composition
Peter Biwer   +6 more
doaj   +1 more source

Vitamin D and thiol-disulfide homeostasis levels in postmenopausal women with overactive bladder syndrome [PDF]

open access: yesJournal of Medical Biochemistry, 2020
Background: This study aimed to find a relationship between vitamin D concentration and thiol-disulfide homeostasis in the pathophysiology of overactive bladder (OAB) syndrome in postmenopausal women. Methods: A total of 76 postmenopausal women, referred
Ustundag Yasemin   +7 more
doaj  

Controlled Cellular Delivery of Amphiphilic Cargo by Redox‐Responsive Nanocontainers

open access: yesAdvanced Science, 2019
The specific transport of amphiphilic compounds such as fluorescently labeled phospholipids into cells is a prerequisite for the analysis of highly dynamic cellular processes involving these molecules, e.g., the intracellular distribution and metabolism ...
Wilke C. deVries   +8 more
doaj   +1 more source

Study of Cytotoxicity and Internalization of Redox-Responsive Iron Oxide Nanoparticles on PC-3 and 4T1 Cancer Cell Lines

open access: yesPharmaceutics, 2022
Redox-responsive and magnetic nanomaterials are widely used in tumor treatment separately, and while the application of their combined functionalities is perspective, exactly how such synergistic effects can be implemented is still unclear.
Timur R. Nizamov   +12 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Optimized methods for preparation of 6I-(ω-sulfanyl-alkylene-sulfanyl)-β-cyclodextrin derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2016
A general high-yielding method for the preparation of monosubstituted β-cyclodextrin derivatives which have attached a thiol group in position 6 is described.
Eva Bednářová   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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