Results 11 to 20 of about 52,814 (284)

Understanding the role of active site residues in CotB2 catalysis using a cluster model

Beilstein Journal of Organic Chemistry, 2020
Terpene cyclases are responsible for the initial cyclization cascade in the multistep synthesis of a large number of terpenes. CotB2 is a diterpene cyclase from Streptomyces melanosporofaciens, which catalyzes the formation of cycloocta-9-en-7-ol, a ...
Keren Raz, Ronja Driller, Thomas Brück, Bernhard Loll, Dan T. Major   +4 more
doaj   +1 more source

Terzyme: a tool for identification and analysis of the plant terpenome. [PDF]

, 2018
BACKGROUND: Terpenoid hydrocarbons represent the largest and most ancient group of phytochemicals, such that the entire chemical library of a plant is often referred to as its 'terpenome'.

core   +3 more sources

Pseudopterosin Biosynthesis: Aromatization of the Diterpene Cyclase Product, Elisabethatriene

Marine Drugs, 2003
: Putative precursors in pseudopterosin biosynthesis, the hydrocarbons isoelisabethatriene (10) and erogorgiaene (11), have been identified from an extract of Pseudopterogorgia elisabethae collected in the Florida Keys.
Amber C. Kohl, Russell G. Kerr
doaj   +1 more source

Diterpenes: Nature's Hidden Gems of Immunomodulation. [PDF]

Int J Mol Sci
Almeida JE, de Oliveira AC, de Castro Alves CE, Filho SMC, de Oliveira ECP, Zuliani JP, Pontes GS.   +6 more
europepmc   +3 more sources

<em>An ent</em>-Kaurane-Type Diterpene in <em>Croton antisyphiliticus</em> Mart.

Molecules, 2012
<em>Croton antisyphiliticus </em>is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract.
Ana Maria Pereira, Suzelei França, Bianca Bertoni, Paulo Pereira, Juliana Coppede, Silvia Taleb-Contini, Sarazete Pereira   +6 more
doaj   +1 more source

Pharmacological Potential of Lathyrane-Type Diterpenoids from Phytochemical Sources

Pharmaceuticals, 2022
Lathyrane diterpenoids are one of the primary types of secondary metabolites present in the genus Euphorbia and one of the largest groups of diterpenes. They are characterized by having a highly oxygenated tricyclic system of 5, 11 and 3 members.
Fátima Vela, Abdellah Ezzanad, Alan Christy Hunter, Antonio José Macías-Sánchez, Rosario Hernández-Galán   +4 more
doaj   +1 more source

Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]

, 2018
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo, A Montalvetti, A Rassi, AB Penissi, AE Eakin, AH Kolien, AJ Solari, AM Sánchez, Ana Yecê das Neves Pinto, C Brack, CF Silva Da, D Gonzalez-Pacanowska, DA Campbell, DA Johnston, DJ Hammond, DV Andrade, E Bontempi, E Lozano, E Lozano, E Lozano, EO Ogbadoiyi, ES Garcia, ES Lozano, F Dos Reis, FR Opperdoes, FR Opperdoes, FR Opperdoes, FS Laranja, H Meyer, H Meyer, J Aldunate, J Lukes, J McKerrow, J Mottram, JA Urbina, JA Urbina, JA Urbina, JA Urbina, JC Engel, JC Linder, JCP Dias, JCP Dias, JD Bergstrom, JD Maya, JF Turrens, JJ Marr, JL Avila, JL Avila, Juliano de Toledo, K Lazardi, K Miranda, K Miranda, KH Lee, L Simpson, LV Muschietti, M Meirelles, M Nieto, MC Elias, MCQB Elias, MR Ariyanayagam, MR Ariyanayagam, NM Sayed El, O Campetella, OS Giordano, OS Giordano, P Barrera, P Webster, PF Pimenta, R Docampo, S Sepúlveda-Boza, SD Brengio, SR Wilkinson, T Souto-Padron, T Souto-Padron, T Souto-Padron, T Souto-Padron, TA Shapiro, TS Tiuman, V Jimenez-Ortiz, V Sülsen, VP Sülsen, VP Sülsen, VV Costantino, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, Wanderley de Souza, WE Gutteridge   +90 more
core   +1 more source

New Labdanes with Antimicrobial and Acaricidal Activity: Terpenes of Callitris and Widdringtonia (Cupressaceae)

Antibiotics, 2020
In spite of the evidence for antimicrobial and acaricidal effects in ethnobotanical reports of Callitris and Widdringtonia, the diterpene acids from Widdringtonia have never been described and no comparison to the Australian clade sister genus Callitris ...
Nicholas J. Sadgrove, Haytham Senbill, Ben-Erik Van Wyk, Ben W. Greatrex   +3 more
doaj   +1 more source

A Review of Diterpenes from Marine-Derived Fungi: 2009–2021

Molecules, 2022
Marine-derived fungi are important sources of novel compounds and pharmacologically active metabolites. As an important class of natural products, diterpenes show various biological activities, such as antiviral, antibacterial, anti-inflammatory ...
Peng Qiu, Jinmei Xia, Haitao Zhang, Donghai Lin, Zongze Shao   +4 more
doaj   +1 more source

Duvatrienediols in cuticular wax of Burley tobacco leaves

Journal of Lipid Research, 1976
4, 8, 13-Duvatriene-1, 3-diol diastereoisomers have been identified in the cuticular wax of fresh Burley tobacco leaves. Their structures were determined by gas-liquid chromatography, mass spectrometry, and infrared and ultraviolet spectroscopy ...
S Y Chang, C Grunwald
doaj   +1 more source