Results 81 to 90 of about 45,446 (245)

Increasing Complexity of a Diterpene Synthase Reaction with a Single Residue Switch [PDF]

, 2008
Terpene synthases often catalyze complex reactions involving intricate series of carbocation intermediates. The resulting, generally cyclical, structures provide initial hydrocarbon frameworks that underlie the astonishing structural diversity of the ...
Determan, Mara, Fulton, D. Bruce, Morrone, Dana, Peters, Reuben, Peters, Reuben, Xu, Meimei   +5 more
core   +3 more sources

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Pushing the limits of concertedness. A waltz of wandering carbocations. [PDF]

, 2019
Among the array of complex terpene-forming carbocation cyclization/rearrangement reactions, the so-called "triple shift" reactions are among the most unexpected.
Castiñeira Reis, Marta, López, Carlos Silva, Nieto Faza, Olalla, Tantillo, Dean J   +3 more
core  

Genome association of carbohydrate metabolites provides new insights toward functional breeding in coffee

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Coffee is one of the world's most widely consumed beverages, derived mainly from Coffea arabica, known for its superior flavor, and Coffea canephora (Robusta/Conilon), valued for its resilience and higher caffeine content. Functional breeding aims to develop cultivars that combine productivity and stress tolerance with improved health‐related ...
Estefania Tavares Flores, Robert Logan Spicer, Elaine M. R. Souza, Maria Amelia G. Ferrão, João Felipe B. Senra, Camila Azevedo, Patricio R. Munoz, Denise Tieman, Cătălin Voiniciuc, Luis Felipe V. Ferrão   +9 more
wiley   +1 more source

Synthesis and Study of the Structure–Activity Relationship of Antiproliferative N-Substituted Isosteviol-Based 1,3-Aminoalcohols

Pharmaceuticals
Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were prepared via stereoselective transformations. The acid-catalysed hydrolysis and rearrangement of natural stevioside produced isosteviol, which was transformed into the ...
Dániel Ozsvár, Noémi Bózsity, István Zupkó, Zsolt Szakonyi   +3 more
doaj   +1 more source

Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea. [PDF]

, 2016
Three new diterpenes, uprolide N (1), uprolide O (2), uprolide P (3) and a known one, dolabellane (4), were isolated from the CH₂Cl₂-MeOH extract of the gorgonian octocoral Eunicea succinea, collected from Bocas del Toro, on the Caribbean coast of Panama.
Fernandez, Patricia L, Gerwick, William H, González, Yisett, Gutiérrez, Marcelino, Guzmán, Héctor M, Gómez-Reyes, José Félix, López-Perez, José Luis, Torres-Mendoza, Daniel   +7 more
core   +2 more sources

Bioconversion of carotenoids into high‐value crocins using a marine sponge carotenoid cleavage dioxygenase

New Phytologist, Volume 250, Issue 5, Page 3230-3246, June 2026.
Summary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Elena Moreno‐Giménez, Lucía Morote, Alberto José López Jiménez, Eduardo Parreño, Jian You Wang, Matteo Nava, Carolina Aguado, Rafael Luján, Salim Al‐Babili, Gianfranco Diretto, Oussama Ahrazem, Lourdes Gómez‐Gómez   +11 more
wiley   +1 more source

Biotransformations of Imbricatolic Acid by Aspergillus niger and Rhizopus nigricans Cultures

Molecules, 2007
Microbial transformation of imbricatolic acid (1) by Aspergillus niger afforded 1α-hydroxyimbricatolic acid (2), while transformation with Rhizopus nigricans yielded 15-hydroxy-8,17-epoxylabdan-19-oic acid (3).
Cristina Theoduloz, Jaime A Rodríguez, Marcela Kurina, Carlos Aranda, Guillermo Schmeda-Hirschmann   +4 more
doaj   +1 more source

A Review of the Anti-diabetic Activity of Andrographis Paniculata (Burm. F.) Nees Based In-vivo Study [PDF]

, 2015
Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life.
Harimurti, S. (Sabtanti), Komalasari, T. (Titi)   +1 more
core  

Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress [PDF]

, 2014
Accepted: 8 January 2014 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Acknowledgments
Alfonso, Amparo, Alonso, Eva, Botana, Luis M, Ebel, Rainer, Houssen, Wael E, Jaspars, Marcel, Leirós, Marta, Rateb, Mostafa E, Rateb, Mostafa Ezzat Mohamed, Sánchez, Jon A   +9 more
core   +4 more sources