Results 81 to 90 of about 10,911 (198)

Identification of clerodane diterpene modifying cytochrome P450 (CYP728D26) in Salvia divinorum ‐ en route to psychotropic salvinorin A biosynthesis

Physiologia Plantarum, Volume 176, Issue 5, September/October 2024.
Abstract Salvia divinorum is a hallucinogenic plant native to the Oaxaca in Mexico. The active ingredient for psychotropic effects in this plant is salvinorin A, a potent and highly selective κ‐opioid receptor agonist. Salvinorin A is distinct from other well‐known opioids, such as morphine and codeine, in that it is a non‐nitrogenous diterpenoid with ...
Iris Ngo, Rahul Kumar, Liang Li, Seon‐Won Kim, Moonhyuk Kwon, Dae‐Kyun Ro   +5 more
wiley   +1 more source

Chemical variability between different organs of the medicinal plant Casearia sylvestris

Revista de Ciências Farmacêuticas Básica e Aplicada, 2020
The phytochemical profile of essential oils and extracts from Casearia sylvestris leaves, flowers and fruits have been investigated here. Leaf and flower extracts were prepared by sonication and analyzed by thin-layer chromatography and high-performance ...
Flávio Alexandre Carvalho, Polyanna Pereira Aguilar, Fernando Bombarda Oda, Helena Sayuri Uchina, Aristeu Gomes Tininis, Eduardo José Crevelin, Antônio Eduardo Miller Crotti, André Gonzaga dos Santos   +7 more
doaj  

Novel Cytotoxic Diterpenes from Casearia arborea

, 2016
Cytotoxicity-guided fractionation of the dichloromethane−methanol extract of the roots of Casearia arborea yielded five novel clerodane diterpenes, casearborins A−E (1−5), as well as cucurbitacin B.
Robert H. Shoemaker (146228), Kate L. McCall (3062049), Delbert L. Herald (2196577), John A. Beutler (7678), Tanya Johnson (3062052), Kathryn Herbert (3062046), Michael R. Boyd (2709340), George R. Pettit (1316853)   +7 more
core   +1 more source

Clerodane Diterpenes from Casearia arguta That Act As Synergistic TRAIL Sensitizers

, 2016
Casearia arguta was investigated as part of the ongoing search for synergistic TRAIL (tumor necrosis factor-α-related apoptosis-inducing ligand) sensitizers.
Thomas J. Sayers (613029), Cheryl L. Thomas (30987), James B. McMahon (7677), Emily L. Whitson (1264857), Curtis J. Henrich (131182), Tawnya C. McKee (2039704)   +5 more
core   +1 more source

Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach

Future Journal of Pharmaceutical Sciences
Background Chronic tinnitus is a complication that affects the central nervous system, specifically the auditory cortex, causing a phantom perception of sounds and noises without any external acoustic stimulus.
Jacilene Silva, Matheus Nunes da Rocha, Victor Moreira de Oliveira, Caio Henrique Alexandre Roberto, Francisco Nithael Melo Lúcio, Márcia Machado Marinho, Hélcio Silva dos Santos, Emmanuel Silva Marinho   +7 more
doaj   +1 more source

Lignans and diterpenes of three Aristolochia species

, 1988
Phytochemical examination of Aristolochia cymbifera, A. esperanzae and A. galeata led to the isolation of furofuran and dibenzylbutyrolactone type lignans, as well as of clerodane and ent-labdane type diterpenes.
Vanderlan da S. Bolzani, Bolzani, Vanderlan da Silva [UNESP], Bolzani, Vanderlan da Silva, Lopes, Lucia M.X. [UNESP], Lucia M.X. Lopes, Lopes, Lucia M.X., Lopes, LMX   +6 more
core   +1 more source

A New ent-Clerodane Diterpene from Hymenaea courbaril var. altissima

Journal of the Brazilian Chemical Society, 2002
A new ent-clerodane and two known ent-labdanes were isolated from the barks of Hymenaea courbaril var. altissima (Ducke). The new diterpene was identified, after esterification with diazomethane, as methyl (-)-(5R,8S,9S,10R)-clerod-3-en-15-oate and known
Nogueira Raquel T., Giacomini Rosana A., Shepherd George J., Imamura Paulo M.   +3 more
doaj  

Bioactive Clerodane Diterpenes from Roots of Carex distachya

, 2010
Two new clerodane diterpenes were isolated from roots of Carex distachya Desf., a perennial plant widely distributed in the coastal area of the Mediterranean basin.
A. IZZO, D'ABROSCA, Brigida, G. DANGELO, FIORENTINO, Antonio, MONACO, Pietro, PACIFICO, Severina   +5 more
core  

Estudo de propriedades químicas, estruturais e biológicas da espécie vegetal Croton urucurana [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pos-Graduação em QuímicaCroton urucurana é uma árvore, pertencente a família Euphorbiaceae, usada na medicina popular no tratamento de dor ...
Zuchinalli, Analice
core  

Clerodendrum trichotomum Thunb.: a review on phytochemical composition and pharmacological activities

Frontiers in Pharmacology
Clerodendrum trichotomum Thunb. (C. trichotomum) is a shrub or tree of the genus Clerodendrum, family Lamiaceae, which is widely distributed in China, Korea, India, Japan and Philippines. C.
Linzhen Li, Linzhen Li, Linzhen Li, Zhiyi Tang, Zhiyi Tang, Shengjia Xiao, Shengjia Xiao, Xiangjie Dai, Xiangjie Dai, Yutong Wang, Yutong Wang, Xi Wei   +11 more
doaj   +1 more source