Ent-Kaurane Diterpenoids from Coffea Genus: An Update of Chemical Diversity and Biological Aspects [PDF]
MoleculesCoffee is one of the most important beverages in the world and is produced from Coffea spp. beans. Diterpenes with ent-kaurane backbones have been described in this genus, and substances such as cafestol and kahweol have been widely investigated, along ...
Víctor de C. Martins +4 more
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Efficient production of clerodane and ent-kaurane diterpenes through truncated artificial pathways in Escherichia coli [PDF]
Beilstein Journal of Organic Chemistry, 2022 The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li +4 more
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Three New Ent-Kaurane Diterpenes with Antibacterial Activity from Sigesbeckia orientalis [PDF]
MoleculesThree novel ent-kaurane diterpenes, namely sigesbeckin A–C (1–3), in conjunction with eight previously identified analogues (4–11), were isolated from Sigesbeckia orientalis. Their chemical structures were resolved through multiple spectroscopic analyses.
Zhong-Shun Zhou +6 more
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Ent-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae) [PDF]
Química Nova, 2012 Phytochemical investigation of the hexane extract from the stem of Xylopia laevigata led to the isolation of the ent-kaurane diterpenoids, ent-kaur-16-en-19-oic acid, 4-epi-kaurenic acid, ent-16β-hydroxy-17-acetoxy-kauran-19-al, ent-3β-hydroxy-kaur-16-en-
Dayanne Meneses Silva +9 more
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Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases [PDF]
Plants, 2023 Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding ...
Nancy Ortiz-Mendoza +5 more
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Methoxylated Flavonols and ent-Kaurane Diterpenes from the South African Helichrysum rutilans and Their Cosmetic Potential [PDF]
Plants, 2023 Chromatographic fractionation of a methanol extract of Helichrysum rutilans afforded seven known compounds. The isolated compounds were identified as 5,7,8-trihydroxy-3,6-dimethoxyflavone-8-O-2-methyl-2-butanoate (C-1), 5,7-dihydroxy-3,6,8 ...
Olugbenga K. Popoola +3 more
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Structure-based drug design studies of the interactions of ent-kaurane diterpenes derived from Wedelia paludosa with the Plasmodium falciparum sarco/endoplasmic reticulum Ca2+-ATPase PfATP6 [PDF]
Memorias do Instituto Oswaldo Cruz, 2015 Malaria is responsible for more deaths around the world than any other parasitic disease. Due to the emergence of strains that are resistant to the current chemotherapeutic antimalarial arsenal, the search for new antimalarial drugs remains urgent though
Daniel Silqueira Martins Guimarães +6 more
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Compounds from Agathis dammara exert hypoglycaemic activity by enhancing glucose uptake: lignans, terpenes and others [PDF]
Natural Products and BioprospectingIn this study, two new kaurane diterpenes (16, 17), together with 12 lignans (1–12), a triterpene (15), and two other compounds (13, 14) were isolated from the woods of Agathis dammara.
Zhe-Wei Yu +11 more
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Diterpenes Isolated from Three Different Plectranthus Sensu Lato Species and Their Antiproliferative Activities against Gynecological and Glioblastoma Cancer Cells. [PDF]
ACS OmegaGáborová M +9 more
europepmc +3 more sources
One amino acid makes the difference: the formation of -kaurene and 16α-hydroxy-kaurane by diterpene synthases in poplar [PDF]
, 2015 BACKGROUND: Labdane-related diterpenoids form the largest group among the diterpenes. They fulfill important functions in primary metabolism as essential plant growth hormones and are known to function in secondary metabolism as, for example ...
Gershenzon, J. +5 more
core +4 more sources