Results 31 to 40 of about 942 (157)

Potential of diterpene compounds as antivirals, a review

Heliyon, 2021
Viruses cause widely transmitted diseases resulting in pandemic conditions. Currently, the world is being hit by the Covid-19 pandemic caused by the SAR-CoV-2 infection. Countries in the world are competing to develop antivirals to overcome this problem.
Andika Pramudya Wardana, Nanik Siti Aminah, Mila Rosyda, Muhammad Ikhlas Abdjan, Alfinda Novi Kristanti, Khun Nay Win Tun, Muhammad Iqbal Choudhary, Yoshiaki Takaya   +7 more
doaj   +1 more source

Kaurane diterpenes protect against apoptosis and inhibition of phagocytosis in activated macrophages [PDF]

British Journal of Pharmacology, 2007
Background and purpose:The kaurane diterpenes foliol and linearol are inhibitors of the activation of nuclear factor κB, a transcription factor involved in the inflammatory response. Effects of these diterpenes on apoptosis and phagocytosis have been analysed in cultured peritoneal macrophages and in the mouse macrophage cell line, RAW 264.7 ...
B, de las Heras, S, Hortelano, N, Girón, P, Bermejo, B, Rodríguez, L, Boscá   +5 more
openaire   +2 more sources

13C-NMR Data of Diterpenes Isolated from Aristolochia Species

Molecules, 2009
The genus Aristolochia,an important source of physiologically active compounds that belong to different chemical classes, is the subject of research in numerous pharmacological and chemical studies.
Antônio Flávio de Carvalho Alcântara, Patrícia Machado de Oliveira, Dorila Piló-Veloso, Alison Geraldo Pacheco   +3 more
doaj   +1 more source

Antimicrobial Activity of Kaurane Diterpenes against Oral Pathogens

Zeitschrift für Naturforschung C, 2008
Two kaurane diterpenes, ent-kaur-16(17)-en-19-oic acid (KA) and 15-β-isovaleryloxy-entkaur- 16(17)-en-19-oic acid (KA-Ival), isolated from Aspilia foliacea, and the methyl ester derivative of KA (KA-Me) were evaluated against oral pathogens.
Sergio R, Ambrosio, Niege A J C, Furtado, Dionéia C R, de Oliveira, Fernando B, da Costa, Carlos H G, Martins, Tatiane C, de Carvalho, Thiago S, Porto, Rodrigo C S, Veneziani   +7 more
openaire   +2 more sources

Green Biosynthesis of Silver Nanoparticles Using Annona glabra and Annona squamosa Extracts with Antimicrobial, Anticancer, Apoptosis Potentials, Assisted by In Silico Modeling, and Metabolic Profiling

Pharmaceuticals, 2022
Annona glabra L. (AngTE) and Annona squamosa L. (AnsTE) fruits have been widely used in cancer treatment. Accordingly, their extracts were used to synthesize silver nanoparticles via a biogenic route (Ang-AgNPs) and (Ans-AgNPs), respectively.
Fatma A. Mokhtar, Nabil M. Selim, Seham S. Elhawary, Soha R. Abd El Hadi, Mona H. Hetta, Marzough A. Albalawi, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Lamiaa I. Fahmy, Rana M. Ibrahim   +10 more
doaj   +1 more source

Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases

Plants, 2023
Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding ...
Nancy Ortiz-Mendoza, Martha Juana Martínez-Gordillo, Emmanuel Martínez-Ambriz, Francisco Alberto Basurto-Peña, María Eva González-Trujano, Eva Aguirre-Hernández   +5 more
doaj   +1 more source

Methoxylated Flavonols and ent-Kaurane Diterpenes from the South African Helichrysum rutilans and Their Cosmetic Potential

Plants, 2023
Chromatographic fractionation of a methanol extract of Helichrysum rutilans afforded seven known compounds. The isolated compounds were identified as 5,7,8-trihydroxy-3,6-dimethoxyflavone-8-O-2-methyl-2-butanoate (C-1), 5,7-dihydroxy-3,6,8 ...
Olugbenga K. Popoola, Jeanine L. Marnewick, Emmanuel I. Iwuoha, Ahmed A. Hussein   +3 more
doaj   +1 more source

Components from the Steamed Leaves of and their Effects on PPAR Activity in HepG2 Cells

Natural Product Communications, 2011
Three ent -kaurane diterpenes ( 1-3 ), four lupane-triterpene glycosides ( 4-7 ), and an oleanane-triterpene glycoside ( 8 ) were isolated from the ethyl acetate and water extracts of the steamed leaves of Acanthopanax koreanum using a combination of ...
Jeong Ah Kim, Seok Bean Song, Seo Young Yang, Young Ho Kim   +3 more
doaj   +1 more source

Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots

Molecules, 2016
Activated microglia are known to be a major source of cellular neuroinflammation which causes various neurodegenerative diseases, including Alzheimer’s disease.
Jung Wha Kim, Ji Yeon Seo, Won Keun Oh, Sang Hyun Sung   +3 more
doaj   +1 more source

Theoretical Research into Anticancer Activity of Diterpenes Isolated from the Paraiban Flora

Natural Product Communications, 2014
Many studies of the scientific literature discuss the anticancer activity of diterpenes inhibiting the Akt/IKK/NF-κB pro-survival signaling cascade, mainly by the activation of serine/threonine phosphatase PP2A.
Luciana Scotti, Hamilton Ishiki, Francisco J.B. Mendonça Junior, Paula F. Santos, Josean F. Tavares, Marcelo S. Silva, Marcus T. Scotti   +6 more
doaj   +1 more source