Occurrence, Biological Activities and Synthesis of Kaurane Diterpenes and their Glycosides [PDF]
Molecules, 2007 This paper presents a review on kaurane diterpenes and their glycoside derivatives, covering aspects of their occurrence, biological activities and the synthesis of these natural products and their analogues. First, it shows and classifies diterpenes, in
Pablo A Garcia +2 more
exaly +7 more sources
The Remarkable Structural Diversity Achieved in ent-Kaurane Diterpenes by Fungal Biotransformations [PDF]
Molecules, 2014 The use of biotransformations in organic chemistry is widespread, with highlights of interesting applications in the functionalization of natural products containing unactivated carbons, like the kaurane diterpenes.
Jacqueline A Takahashi +2 more
exaly +6 more sources
Ent-Kaurane Diterpenoids from Coffea Genus: An Update of Chemical Diversity and Biological Aspects [PDF]
MoleculesCoffee is one of the most important beverages in the world and is produced from Coffea spp. beans. Diterpenes with ent-kaurane backbones have been described in this genus, and substances such as cafestol and kahweol have been widely investigated, along ...
Víctor de C. Martins +4 more
doaj +3 more sources
Three New Cytotoxic ent-Kaurane Diterpenes from Isodon excisoides [PDF]
Molecules, 2015 Three types of ent-kaurane diterpenoids were isolated from the aerial parts of Isodon excisoides, including three new diterpenoids, 1α,7α,14β-trihydroxy-20-acetoxy-ent-kaur-15-one (1); 1α,7α,14β,18-tetrahydroxy-20-acetoxy-ent-kaur-15-one (2); and 1α ...
Li-Ping Dai +6 more
doaj +4 more sources
Trachylobane and kaurane diterpenes from Croton floribundus spreng [PDF]
Química Nova, 2013 A new trachylobane diterpene ent-trachyloban-18,19-diol (1) was isolated from root bark of Croton floribundus, along with known diterpenes ent-trachyloban-19-oic acid (2), 15b-hydroxy-ent-trachyloban-19-oic acid (3), ent-trachyloban-19-ol (4), ent-kaur ...
Paula Karina S. Uchôa +8 more
doaj +4 more sources
Three New Ent-Kaurane Diterpenes with Antibacterial Activity from Sigesbeckia orientalis [PDF]
MoleculesThree novel ent-kaurane diterpenes, namely sigesbeckin A–C (1–3), in conjunction with eight previously identified analogues (4–11), were isolated from Sigesbeckia orientalis. Their chemical structures were resolved through multiple spectroscopic analyses.
Zhong-Shun Zhou +6 more
doaj +3 more sources
Mechanistic Pathways and Molecular Targets of Plant-Derived Anticancer ent-Kaurane Diterpenes [PDF]
Biomolecules, 2020 Since the first discovery in 1961, more than 1300 ent-kaurane diterpenoids have been isolated and identified from different plant sources, mainly the genus Isodon. Chemically, they consist of a perhydrophenanthrene subunit and a cyclopentane ring.
Md. Shahid Sarwar +4 more
doaj +4 more sources
Identification of Kaurane-Type Diterpenes as Inhibitors of Leishmania Pteridine Reductase I [PDF]
Molecules, 2021 The current treatments against Leishmania parasites present high toxicity and multiple side effects, which makes the control and elimination of leishmaniasis challenging.
Chonny Herrera-Acevedo +5 more
doaj +3 more sources
-Kaurane Diterpenes from and Their Cytotoxic Activities [PDF]
Natural Product Communications, 2014 A new ent -kaurane glycoside, annoglabasin H ( 1 ), and three known ent -kauranes, annoglabasin E ( 2 ), annoglabasin B ( 3 ), and 19-nor- ent -kaurent-4-ol-17-oic acid ( 4 ) were isolated from the fruits of Annona glabra .
Hoang Le Tuan Anh +9 more
doaj +3 more sources
Cafestol-derivatives as potential FXR agonists and CYP7A1 inhibitors and their impact on hypercholesterolemia: an in silico study [PDF]
Scientific ReportsCafestol is a hypercholesterolemic ent-kaurane diterpene found in unfiltered coffee, a regular component of the human diet. This diterpene is reported to modulate macromolecules involved in cholesterol metabolism, such as the farnesoid X receptor (FXR ...
Maria Alice Esteves da Silva +5 more
doaj +2 more sources