Results 1 to 10 of about 942 (157)
Occurrence, Biological Activities and Synthesis of Kaurane Diterpenes and their Glycosides [PDF]
Molecules, 2007 This paper presents a review on kaurane diterpenes and their glycoside derivatives, covering aspects of their occurrence, biological activities and the synthesis of these natural products and their analogues. First, it shows and classifies diterpenes, in
Alaide Braga De Oliveira +2 more
exaly +6 more sources
Three New Cytotoxic ent-Kaurane Diterpenes from Isodon excisoides [PDF]
Molecules, 2015 Three types of ent-kaurane diterpenoids were isolated from the aerial parts of Isodon excisoides, including three new diterpenoids, 1α,7α,14β-trihydroxy-20-acetoxy-ent-kaur-15-one (1); 1α,7α,14β,18-tetrahydroxy-20-acetoxy-ent-kaur-15-one (2); and 1α ...
Wang Zhi-Min
exaly +5 more sources
Food Science &Nutrition, Volume 11, Issue 9, Page 5409-5426, September 2023., 2023 The use of natural antioxidants in meat products has been extensively studied. However, no reports have been found regarding the accumulation of antioxidant residues in meat products over the storage time in cold storage by LC‐DAD‐MS analysis. To manufacture of Punica granatum L.
Elahe Abedi +4 more
wiley +1 more source
Plant terpene specialized metabolism: complex networks or simple linear pathways?
The Plant Journal, Volume 114, Issue 5, Page 1178-1201, June 2023., 2023 SUMMARY From the perspectives of pathway evolution, discovery and engineering of plant specialized metabolism, the nature of the biosynthetic routes represents a critical aspect. Classical models depict biosynthesis typically from an end‐point angle and as linear, for example, connecting central and specialized metabolism. As the number of functionally
Emily R. Lanier +2 more
wiley +1 more source
Medicinal Research Reviews, Volume 43, Issue 3, Page 614-682, May 2023., 2023 Abstract Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight cancer and overcome drug resistance in antitumor therapy. Understanding the molecular interactions and structural features of ferroptosis‐inducing compounds might ...
Solveigh C. Koeberle +3 more
wiley +1 more source
Risks for human health related to the presence of grayanotoxins in certain honey
EFSA Journal, Volume 21, Issue 3, March 2023., 2023 Abstract The European Commission asked EFSA for a scientific opinion on the risks for human health of the presence of grayanotoxins (GTXs) in ‘certain honey’ from Ericaceae plants. The risk assessment included all structurally related grayananes occurring with GTXs in ‘certain’ honey. Oral exposure is associated with acute intoxication in humans. Acute
EFSA Panel on Contaminants in the Food Chain (CONTAM) +24 more
wiley +1 more source
Labdane conjugates protect cardiomyocytes from doxorubicin‐induced cardiotoxicity
Drug Development Research, Volume 84, Issue 1, Page 84-95, February 2023., 2023 Abstract The cardiovascular side effects associated with doxorubicin (DOX), a wide spectrum anticancer drug, have limited its clinical application. Therefore, to explore novel strategies with cardioprotective effects, a series of new labdane conjugates were prepared (6a–6c and 8a–8d) from the natural diterpene labdanodiol (1).
Irene Cuadrado +6 more
wiley +1 more source
Journal of Immunology Research, Volume 2023, Issue 1, 2023., 2023 The morbidity of oral cancer is high in the world. Oridonin is a traditional Chinese medicine that can effectively inhibit oral squamous cell carcinoma (OSCC) growth, but its mechanism remains unclear. Our previous data showed that oridonin inhibited CAL‐27 cell proliferation and promoted apoptosis.
Guohui Wu +9 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2022 The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li +4 more
doaj +1 more source
EFSA Journal, Volume 20, Issue 5, May 2022., 2022 Abstract The EFSA Panel on Food Additives and Flavourings (FAF Panel) provides a scientific opinion on the safety of a proposed amendment of the specifications of enzymatically produced steviol glycosides (E 960c) with respect to the inclusion of rebaudioside D produced via enzyme‐catalysed bioconversion of purified stevia leaf extract. Rebaudioside D (
EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings) +26 more
wiley +1 more source