Occurrence, Biological Activities and Synthesis of Kaurane Diterpenes and their Glycosides [PDF]
Molecules, 2007 This paper presents a review on kaurane diterpenes and their glycoside derivatives, covering aspects of their occurrence, biological activities and the synthesis of these natural products and their analogues. First, it shows and classifies diterpenes, in
Pablo Anselmo García García +2 more
exaly +6 more sources
Three New Ent-Kaurane Diterpenes with Antibacterial Activity from Sigesbeckia orientalis [PDF]
MoleculesThree novel ent-kaurane diterpenes, namely sigesbeckin A–C (1–3), in conjunction with eight previously identified analogues (4–11), were isolated from Sigesbeckia orientalis. Their chemical structures were resolved through multiple spectroscopic analyses.
Zhong-Shun Zhou +6 more
doaj +4 more sources
The Remarkable Structural Diversity Achieved in ent-Kaurane Diterpenes by Fungal Biotransformations [PDF]
Molecules, 2014 The use of biotransformations in organic chemistry is widespread, with highlights of interesting applications in the functionalization of natural products containing unactivated carbons, like the kaurane diterpenes.
Jacqueline A Takahashi +1 more
exaly +5 more sources
Ent-Kaurane Diterpenoids from Coffea Genus: An Update of Chemical Diversity and Biological Aspects [PDF]
MoleculesCoffee is one of the most important beverages in the world and is produced from Coffea spp. beans. Diterpenes with ent-kaurane backbones have been described in this genus, and substances such as cafestol and kahweol have been widely investigated, along ...
Víctor de C. Martins +4 more
doaj +2 more sources
Efficient production of clerodane and ent-kaurane diterpenes through truncated artificial pathways in Escherichia coli [PDF]
Beilstein Journal of Organic Chemistry, 2022 The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li +4 more
doaj +2 more sources
Ent-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae) [PDF]
Química Nova, 2012 Phytochemical investigation of the hexane extract from the stem of Xylopia laevigata led to the isolation of the ent-kaurane diterpenoids, ent-kaur-16-en-19-oic acid, 4-epi-kaurenic acid, ent-16β-hydroxy-17-acetoxy-kauran-19-al, ent-3β-hydroxy-kaur-16-en-
Dayanne Meneses Silva +9 more
doaj +6 more sources
Cafestol-derivatives as potential FXR agonists and CYP7A1 inhibitors and their impact on hypercholesterolemia: an in silico study [PDF]
Scientific ReportsCafestol is a hypercholesterolemic ent-kaurane diterpene found in unfiltered coffee, a regular component of the human diet. This diterpene is reported to modulate macromolecules involved in cholesterol metabolism, such as the farnesoid X receptor (FXR ...
Maria Alice Esteves da Silva +5 more
doaj +2 more sources
Compounds from Agathis dammara exert hypoglycaemic activity by enhancing glucose uptake: lignans, terpenes and others [PDF]
Natural Products and BioprospectingIn this study, two new kaurane diterpenes (16, 17), together with 12 lignans (1–12), a triterpene (15), and two other compounds (13, 14) were isolated from the woods of Agathis dammara.
Zhe-Wei Yu +11 more
doaj +2 more sources
One amino acid makes the difference: the formation of -kaurene and 16α-hydroxy-kaurane by diterpene synthases in poplar [PDF]
, 2015 BACKGROUND: Labdane-related diterpenoids form the largest group among the diterpenes. They fulfill important functions in primary metabolism as essential plant growth hormones and are known to function in secondary metabolism as, for example ...
Gershenzon, J. +5 more
core +4 more sources
Diterpenes Isolated from Three Different Plectranthus Sensu Lato Species and Their Antiproliferative Activities against Gynecological and Glioblastoma Cancer Cells. [PDF]
ACS OmegaGáborová M +9 more
europepmc +3 more sources