Broussonetia papyrifera Root Bark Extract Exhibits Anti-inflammatory Effects on Adipose Tissue and Improves Insulin Sensitivity Potentially Via AMPK Activation [PDF]
The chronic low-grade inflammation in adipose tissue plays a causal role in obesity-induced insulin resistance and its associated pathophysiological consequences. In this study, we investigated the effects of extracts of Broussonetia papyrifera root bark
Choi, Jang Hyun +9 more
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Four New ent-Kaurane Diterpene Glycosides from Isodon henryi
To obtain diterpene glycosides from an aqueous extract of the aerial parts of Isodon henryi and further investigate their cytotoxicities, in this study, a total of seven compounds were isolated, including six ent-kaurane diterpene glycosides (1−6 ...
Ya-Lin Liu +6 more
doaj +1 more source
Diterpene Synthases and Their Responsible Cyclic Natural Products [PDF]
This review provides an overview of diterpene synthases which were initially identified via genetic and/or biochemical means, traversing all organisms researched to ...
Hai-Yan Gong, Xiao-Ya Chen, Ying Zeng
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Aldama discolor (syn.Viguiera discolor) is an endemic Asteraceae from the Brazilian “Cerrado”, which has not previously been investigated for its chemical constituents and biological activity.
Mauro S. Nogueira +4 more
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An overview of the traditional use, phytochemistry, and biological activity of the genus Homalanthus [PDF]
Homalanthus species are native to tropical Asia and the Pacific region. This genus, comprising 23 accepted species, received less scientific attention compared to other genera of the Euphorbiaceae family. Seven Homa-lanthus species, such as H. giganteus,
Hohmann Judit, Wirasisya Dyke Gita
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Diversity of the diterpenes in the leaves of Xylopia laevigata (Annonaceae) and their cytotoxicities
The phytochemical investigation of the hexane extract which was obtained from the leaves of Xylopia laevigata (Annonaceae) produced six terpenes. Among these, five diterpenes named abieta-7,13-dien-3-one, ent-7β-acetoxy-16β-hydroxy-kaurane, 4-epi ...
Emmanoel V. Costa +10 more
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SYNTHETIC TRANSFORMATIONS OF ENT-KAURENOIC ACID [PDF]
This paper presents a review on kaurane diterpenes, covering various aspects of chemical and microbiological transformations of native ent-kaurenoic acid, namely, its reactions via COOH groups, double bonds and rearrangements of the carbon skeleton that ...
Olga Morarescu
doaj
Casbane diterpene as a promising natural antimicrobial agent against biofilm-associated infections [PDF]
Croton nepetaefolius is a native plant from northeastern Brazil that belongs to the Euphorbiaceae family. The biological action of this plant has been extensively explored, being the secondary metabolites responsible for its properties alkaloids ...
Benildo Sousa Cavada +18 more
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STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF DITERPENES FOR TREATMENT OF ALZHEIMER'S DISEASE
Alzheimer's disease is an irreversible, degenerative and age-related disease which is growing more and more with the increase in life expectancy. Kaurane diterpenes are a class of natural products available in large amounts in nature and isolated from ...
Gabriel F. dos Santos +8 more
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Chemistry of South African Lamiaceae: Structures and Biological Activity of Terpenoids [PDF]
South Africa flora is one of the most important mega floras with high endemic species percentage. Lamiaceae is an important family in South Africa with ±308 species in 41 genera and contains many important plants (~23%) traditionally used for treatment ...
Hussein, Ahmed A.
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