Results 61 to 70 of about 39,725 (232)

Antiplatelet and Anticoagulant Effects of Diterpenes Isolated from the Marine Alga, Dictyota menstrualis

Marine Drugs, 2014
Cardiovascular diseases represent a major cause of disability and death worldwide. Therapeutics are available, but they often have unsatisfactory results and may produce side effects.
Laura de Andrade Moura, Ana Carolina Marqui de Almeida, Thaisa Francielle Souza Domingos, Fredy Ortiz-Ramirez, Diana Negrão Cavalcanti, Valéria Laneuville Teixeira, André Lopes Fuly   +6 more
doaj   +1 more source

Synergistic Modulation of Lipid Levels by Coffee and Swimming With Evidence of a Strong Obesity-Dyslipidemia Link: A Preclinical Study. [PDF]

Int J Food Sci
Obesity is a major global health concern closely associated with metabolic disorders, particularly dyslipidemia. Lifestyle interventions such as dietary modification and physical activity can improve lipid regulation. However, the combined effects of coffee intake and exercise on lipid level remain unclear.
Yusni Y, Yusuf H, Murzalina C, Mahmudati N.   +3 more
europepmc   +2 more sources

Is the endophyte‐based plant protection against aphids mediated by changes in the insect microbiome?

Insect Science, EarlyView.
We showed that the fungal endophyte Epichloë strain AR37 increased the plant resistance against aphids via the production of indole diterpene alkaloids. The reduction in aphid performance was not associated with changes in abundance/composition/diversity of the insect's bacterial microbiota, but additional endophyte effects on this microbiota cannot be
Daniel A. Bastías, Luis Carvalho, Ruy Jáuregui, Richard D. Johnson, Wei Zhang, Pedro E. Gundel   +5 more
wiley   +1 more source

Labdane-Type Diterpenes, Galangalditerpenes A–C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga

Molecules, 2017
In our continuing study of biologically active natural products from the fruit of Alpinia galanga (Zingiberaceae), we newly isolated three new labdane-type diterpenes, termed galangalditerpenes A–C (1–3), along with four known sesquiterpenes (4–7) and ...
Yoshiaki Manse, Kiyofumi Ninomiya, Ryosuke Nishi, Yoshinori Hashimoto, Saowanee Chaipech, Osamu Muraoka, Toshio Morikawa   +6 more
doaj   +1 more source

Antibacterial Natural Halimanes: Potential Source of Novel Antibiofilm Agents

Molecules, 2020
The development of new agents against bacteria is an urgent necessity for human beings. The structured colony of bacterial cells, called the biofilm, is used to defend themselves from biocide attacks.
Ignacio E. Tobal, Alejandro M. Roncero, Rosalina F. Moro, David Díez, Isidro S. Marcos   +4 more
doaj   +1 more source

Recent Updates on the Functional Impact of Kahweol and Cafestol on Cancer

Molecules, 2022
Kahweol and cafestol are two diterpenes extracted from Coffea arabica beans that have distinct biological activities. Recent research describes their potential activities, which include anti-inflammatory, anti-diabetic, and anti-cancer properties, among ...
Salma Eldesouki, Rama Qadri, Rashid Abu Helwa, Hiba Barqawi, Yasser Bustanji, Eman Abu-Gharbieh, Waseem El-Huneidi   +6 more
doaj   +1 more source

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products

The FEBS Journal, EarlyView.
We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink, Joshua N. Whitehead, Linus O. Johannissen, Nigel S. Scrutton   +3 more
wiley   +1 more source

Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical periodontitis (AP) and apical periodontitis with copaiba administration (AP + COP).
Rayssa Maitê Farias Nazário, Deborah Ribeiro Frazão, Leonardo Oliveira Bittencourt, Victoria Santos Chemelo, José Mário Matos‐Sousa, Beatriz Rodrigues Risuenho Peinado, Roberta Souza D’almeida Couto, Osmar Alves Lameira, João Daniel Mendonça de Moura, Jorddy Neves Cruz, Fabrício Mezzomo Collares, Rafael Rodrigues Lima   +11 more
wiley   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

Journal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac, Milica Milutinović, Dragana Matekalo, Neda Popović, Luka Petrović, Uroš Gašić, Marijana Skorić, Branislav Šiler, Tamara Lukić, Ana Stupar, Slavica Dmitrović, Jasmina Nestorović Živković, Biljana Filipović, Jelena Božunović, Miloš Todorović, Danijela Mišić   +15 more
wiley   +1 more source

Computer-Aided Chemotaxonomy and Bioprospecting Study of Diterpenes of the Lamiaceae Family

Molecules, 2019
Lamiaceae is one of the largest families of angiosperms and is classified into 12 subfamilies that are composed of 295 genera and 7775 species. It presents a variety of secondary metabolites such as diterpenes that are commonly found in their species ...
Andreza Barbosa Silva Cavalcanti, Renata Priscila Costa Barros, Vicente Carlos de Oliveira Costa, Marcelo Sobral da Silva, Josean Fechine Tavares, Luciana Scotti, Marcus Tullius Scotti   +6 more
doaj   +1 more source