Results 81 to 90 of about 14,560 (215)

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase‐Like Genes From Springtails

Angewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang, Clement Schneider, Zarley Rebholz, Stefan Schulz, Kathy Darragh, Jeroen S. Dickschat   +5 more
wiley   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, Volume 38, Issue 59, 22 October 2026.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Synergistic Cytotoxicity of Cafestol and Kahweol With Doxorubicin in Breast Cancer Cells Involves TNF‑α Targeting and NF‑κB Downregulation

Archiv der Pharmazie, Volume 359, Issue 10, October 2026.
Cafestol and kahweol (C&K) are cytotoxic to breast cancer cells and have a synergistic effect with doxorubicin. C&K interact with TNF‐α and downregulate the TNF‐α/NF‐κB pathway, underscoring their therapeutic potential for breast cancer. NIAID Visual & Medical Arts. Generic Cells. NIAID NIH BIOART Source. bioart.niaid.nih.gov/bioart/171. NIAID Visual &
Layane D. Souza, Fábio Junior M. Novaes, Carlos Luan A. Passos, Ísis S. S. de Amorim, Pedro Nicolau‐Neto, Juliana A. Rodrigues, Adilson F. Teixeira, Christian Ferreira, Nathalia Alexia N. dos Santos, Priscila G. Camargo, Marcelle L. F. Bispo, Camilo Henrique S. Lima, Bruno Ricardo B. Pires, Adenilson de Sousa da Fonseca, Claudia M. Rezende, Eliane Fialho, Andre Luiz Mencalha   +16 more
wiley   +1 more source

Fragment‐Linked Purine Derivatives as Inhibitors of (p)ppGpp Synthetases: Design, Synthesis, and Structure‐Activity Relationships

Archiv der Pharmazie, Volume 359, Issue 10, October 2026.
Fragment‐linked purine derivatives were designed to mimic nucleotide binding in bacterial (p)ppGpp synthetases. Structure‐guided optimization enabled selective inhibition of Staphylococcus aureus SAS1, revealing a new chemical strategy for targeting the stringent response and mechanisms of bacterial persistence.
Rayan Aboalgasim Makawi Abdalrahman, Katharina Sophie Erlitz, Joana Massa, Christopher‐Nils Mais, Gert Bange, Anna Junker, Oliver Koch   +6 more
wiley   +1 more source

Dodonaea viscosa in Breast Cancer: Phytochemistry, Anticancer Mechanisms, and Emerging Immunotherapeutic and Translational Perspectives

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Breast cancer remains a leading cause of cancer‐related mortality among women worldwide, with treatment resistance, disease heterogeneity, and therapy‐associated toxicities limiting clinical outcomes. Its major clinically relevant subtypes, including oestrogen receptor‐positive (ER+), human epidermal growth factor receptor 2‐positive (HER2 ...
Nireshini Reddy, Catherine H. Kaschula, Nokwanda P. Makunga, Willem Jacobus Perold, Sanjeev Rambharose, Anna‐Mart Engelbrecht   +5 more
wiley   +1 more source

Cyclopiane Suppresses Gastric Cancer Invasion and Angiogenesis via the CYR61/αvβ3 Integrin/NF‐κB Pathway

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Cysteine‐rich angiogenic inducer 61 (CYR61), a matricellular protein, has been implicated in gastric cancer aggressiveness through activation of integrin‐mediated NF‐κB signaling; however, effective pharmacological strategies targeting this axis remain limited.
Yingfeng Zhang, Hongjun Tian, Song Wang, Feng Lin, Weixiang Li, Runben Jiang, Zhengxuan Jiang, Wenbin Wang   +7 more
wiley   +1 more source

Mass Spectrometric Studies of Diterpenes. 6. Aromatic Diterpenes. [PDF]

Acta Chemica Scandinavica, 1969
C. R. Enzell, I. Wahlberg, S. Liaaen-Jensen, Richard Evans Schultes, Alf A. Lindberg, Gert Jansen, Bo Lamm, Benny Samuelsson   +7 more
openaire   +2 more sources

Metabolomic Analysis Uncovers the Presence of Pimarenyl Cation-Derived Diterpenes as Insecticidal Constituents of Sphagneticola trilobata

Plants
Aphis gossypii is a significant global pest that impacts numerous agricultural crops and vegetables, causing direct damage to food plants and indirect damage through the transmission of phytopathogenic viruses, primarily begomoviruses.
Lilia Chérigo, Juan Fernández, Ramy Martínez, Sergio Martínez-Luis   +3 more
doaj   +1 more source

Detection of the Hepatotoxins, Carboxyparquin and Parquin, in Cestrum, Sessea, and Vestia Species (Solanaceae)

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Several species within the tribe, Cestreae, are implicated in being hepatotoxic to livestock. Carboxyparquin and/or parquin are implicated as the toxic principles. Herbarium vouchers are useful resources to screen for the occurrence of these toxins in species of Cestrum, Sessea, and Vestia.
Stephen T. Lee, Michael H. Nee, Daniel G. Ubiali, Franklin Riet‐Correa, Mizael Machado, Daniel Cook   +5 more
wiley   +1 more source

Phytochemical Fingerprinting of Sanchezia nobilis Hook. F. Leaf Extract and Evaluation of Anxiolytic, Cytotoxic, and Antioxidant Activities In Vivo, In Vitro, and In Silico

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
GC‐MS fingerprinting demonstrated that ethanolic leaf extract of Sanchezia nobilis (SNE) many phytochemicals out of which aniline and isoquinoline showed potential binding affinity to alpha1GABAA receptor responsible for anxiolytic effects. In vitro studies confirmed antioxidant effects of SNE.
Progga Paramita Paul, Musfiqur Rahman Sakib, Pritam Kundu, Dabashis Chakraborty, Tasnim Fatema, Shahriar Hossen, Ahsan Abid, Trina Mitra, Manik Chandra Shill, Utpal Kumar Karmakar   +9 more
wiley   +1 more source