Results 51 to 60 of about 42,510 (249)

DREADD agonist compound 21 causes acute diuresis in wild-type mice

Frontiers in Pharmacology
The targeted activation or inhibition of specific cell populations using chemogenetics allows the precise dissection of cellular signaling and function.
Bryce MacIver, Ali Wu, Warren G. Hill, Weiqun Yu   +3 more
doaj   +1 more source

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone, Erik Moedt, Hiddo J. L. Heerspink, Michael J. Davies, Manon Girard, David Z. I. Cherney, Marcel H. A. Muskiet   +6 more
wiley   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus, Piort Gajewski, Piotr Ponikowski   +2 more
wiley   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Evaluating Nurses' Perspectives on the Acceptability and Practicality of Comfort Rounding for Personalised Nutritional and Mobility Care in Surgical Wards: A Mixed‐Methods Feasibility Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To evaluate nurses' perspectives on factors influencing the acceptability and practicality of comfort rounding, focussing on personalised nutritional and mobility care. Design Mixed‐methods feasibility study. Methods Focus group interviews with nurses were conducted before, during and at the end of the implementation period (2022–2023).
Femke Becking‐Verhaar, Fanny Pelzer, Harm Van Noort, Cariline Roosen, Yvonne Van Eijk‐Hustings, Marian De Van Der Schueren, Hester Vermeulen, Getty Huisman‐De Waal   +7 more
wiley   +1 more source

GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation [PDF]

, 2020
Kenichi Katsurada, Shyam Sundar Nandi, Hong Zheng, Xuefei Liu, Neeru M. Sharma, Kaushik P. Patel   +5 more
openalex   +1 more source

COVID‐19 and diabetic ketoacidosis: National outcomes, predictors, and resource utilization in the United States

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background The impact of COVID‐19 infection on diabetic ketoacidosis (DKA) outcomes remains incompletely characterized at a national level. Methods We analyzed adult DKA hospitalizations in the United States from the 2020–2021 National Inpatient Sample.
Jia Ee Chia, Song Peng Ang, Luis Chozet, Eunseuk Lee, Jose Iglesias   +4 more
wiley   +1 more source

Effect of Diuretics on Ureteral Stone Therapy with Extracorporeal Shock Wave Lithotripsy

Saudi Journal of Kidney Diseases and Transplantation, 2008
To evaluate the effect of diuretics on ureteral stone fragmentation and clearance during therapy with extra corporeal shock wave lithotripsy (ESWL), we studied 87 patients with ureteral stone at different levels and treated with ESWL.
Zomorrodi A, Golivandan J, Samady J
doaj  

Tridax procumbens Linn. leaf extract promotes diuresis and reduces blood pressure in Deoxycorticosterone acetate-induced hypertensive male wistar rats

Journal of Research in Traditional Medicine
Background: Anti-hypertensive potentials of Tridax procumbens have been documented ex vivo. There is, however, a dearth of information on its effect in hypertensive rats.
Grace O Isehunwa, Shehu-Tijani T Shittu, Olusegun D Alaga, Husein M Salahdeen, AbdulRasak A Alada   +4 more
doaj   +1 more source

Does plasma ANP participate in natriuresis induced by a-MSH?

Brazilian Journal of Medical and Biological Research, 1997
a-Melanocyte-stimulating hormone (a-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of a-
D.L.W. Picanço-Diniz, G. Ribeiro-Oliveira, A.L.V. Favaretto, J. Gutkowska, S.M. McCann, J. Antunes-Rodrigues   +5 more
doaj   +1 more source