Results 51 to 60 of about 5,417,325 (244)

Inpatient Diuretic Management of Acute Heart Failure: A Practical Review

, 2021
The inpatient treatment of acute heart failure (AHF) is aimed at achieving euvolemia, relieving symptoms, and reducing rehospitalization. Adequate treatment of AHF is rooted in understanding the pharmacokinetics and pharmacodynamics of select diuretic ...
Sakr, Antoine, Ali, Saif, Jung, Sharon, Nandkeolyar, Shuktika, Stoletniy, Liset, Abramov, Dmitry, Hilliard, Anthony, VERBRUGGE, Frederik, Saif Ali   +8 more
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Diuretic response in acute heart failure-an analysis from ASCEND-HF

, 2015
Background Diuretic unresponsiveness often occurs during hospital admission for acute heart failure (AHF) and is associated with adverse outcome. This study aims to investigate determinants, clinical outcome, and the effects of nesiritide on diuretic ...
O'Connor, Christopher M., Damman, Kevin; id_orcid, Hernandez, Adrian F., Voors, Adriaan A., Testani, Jeffrey M., Starling, Randall C., Ezekowitz, Justin A., ter Maaten, Jozine M., Tang, W. H. Wilson, Dunning, Allison M., Damman, Kevin, Valente, Mattia A. E., Califf, Robert M., Schulte, Phillip J., van der Meer, Peter   +14 more
core   +1 more source

Additional file 1 of Doppler study of portal vein and renal venous velocity predict the appropriate fluid response to diuretic in ICU: a prospective observational echocardiographic evaluation

, 2022
Additional file 1: Table S1. Hemodynamic and echocardiographic measurements according to congestive response to diuretic treatment (Appropriate fluid depletion vs Control). $p 
Pierre-Grégoire Guinot (5900429), Pierre-Alain Bahr (13915937), Vivien Berthoud (5875010), Maxime Nguyen (5875019), Vincenza Caruso (12898478), Belaid Bouhemad (5875046), Bogdan A. Popescu (12121365), Stefan Andrei (4482892), Paul-Michel Mertes (8498475)   +8 more
core   +1 more source

Diuretic Resistance Management in a Patient with Type I Cardiorenal Syndrome: A Case Report [PDF]

, 2021
Diuretic resistance is commonly found as a problem in acute heart failure (AHF). A further understanding of diuretic response could lead to improved personal approaches for treating patients with AHF.
Hendri Susilo, -, Mochamad Yusuf Alsagaff, -   +1 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Preferred Diuretic Therapy in Primary Hypertension: Chlorthalidone or Hydrochlorothiazide?

, 2023
Chlorthalidone is recommended as the preferred diuretic therapy for primary hypertension. However, results from multiple studies suggest an equivalent response when compared to hydrochlorothiazide.
Young, Trevor
core   +1 more source

Spot urine sodium‐to‐creatinine ratio surpasses sodium in identifying poor diuretic response in acute heart failure

ESC Heart Failure
Aims We aim to identify the most accurate marker for early prediction of poor diuretic response in acute heart failure (AHF) patients with signs of congestion requiring intravenous diuretic treatment.
Gracjan Iwanek, Mateusz Guzik, Robert Zymliński, Marat Fudim, Piotr Ponikowski, Jan Biegus   +5 more
doaj   +1 more source

Genetic variation in diuretic responses: further and correlated responses to selection

Genetical Research, 1967
Three parameters of diuretic response to water-load (diuretic lag, maximum rate of diuresis and ratio of total output to input volume) have each responded to selection from a genetically heterogeneous base stock with significant realized heritabilities.
J, Stewart, S G, Spickett
openaire   +2 more sources

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source