Results 91 to 100 of about 176,126 (218)

Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]

, 2016
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H., Dominiczak, Anna F., Mccallum, Linsay, Muir, Scott, Padmanabhan, Sandosh, Smith, Daniel J., Touyz, Rhian M.   +6 more
core   +1 more source

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use

Clinical Pharmacology &Therapeutics, EarlyView.
The impact of the choice of common data model (CDM) approach on the study results in a real‐world evidence (RWE) study is unknown. We aimed to determine potential differences in the results of an RWE study when data were mapped to two different CDMs, ConcePTION and OMOP. With the same instance of CPRD GOLD, data were mapped to both CDMs. Using the same
Nicholas B. Hunt, Patrick Souverein, Marloes Bazelier, Nicola Barclay, Antonella Delmestri, Miriam Sturkenboom, Daniel Prieto‐Alhambra, Helga Gardarsdottir, Olaf Klungel   +8 more
wiley   +1 more source

Women have a higher risk of hospital admission associated with hyponatremia than men while using diuretics

Frontiers in Pharmacology
BackgroundHyponatremia is a common electrolyte disturbance and known adverse drug reaction of diuretics. Women tend to be more susceptible for diuretic associated hyponatremia.
L. C. Hendriksen, L. C. Hendriksen, M. S. Mouissie, M. S. Mouissie, R. M. C. Herings, R. M. C. Herings, P. D. van der Linden, L. E. Visser, L. E. Visser, L. E. Visser   +9 more
doaj   +1 more source

Peripartum cardiomyopathy: diagnosis and management [PDF]

, 2017
No abstract ...
Coats, Caroline J., Dalzell, Jonathan R., Jackson, Alice M., Jhund, Pardeep S., Petrie, Mark C., Walker, Niki L.   +5 more
core   +1 more source

Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri, Islam R. Younis, Shadia I. Jalal, Theodore F. Logan, Rohan Maniar, Steven M. Bray, Sara K. Quinney, Zeruesenay Desta, Todd C. Skaar, James E. Tisdale, Tyler Shugg   +10 more
wiley   +1 more source

Xerostomía causada por el consumo de diuréticos en pacientes hipertensos

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: la xerostomía, o síndrome de boca seca, afecta principalmente a pacientes ancianos. Por sí misma no parece estar relacionada directamente con la edad, sino con las enfermedades o fármacos que se suelen administrar en esa etapa de la vida ...
Yolexis Pérez Espinosa, Maydelyn Ureña Espinosa, Yadira Rodríguez González, Karina Bosch Utra, Tamara Portelles Morales   +4 more
doaj  

Spleen white pulp structural and cellular composition in experimental furosemide-­induced hypomagnesemia

RUDN Journal of Medicine
Relevance. Magnesium deficiency in the blood (hypomagnesemia) is due to many reasons, among which loop diuretics (furosemide) occupy acertain place. The role of the spleen in this process has not been determined.
Marina V. Smetanina, Natalya N. Chuchkova, Natalya V. Kormilina, Ksenia A. Pazinenko   +3 more
doaj   +1 more source

Pharmacological and toxicological aspects of doping substances and the role of the sports pharmacist [PDF]

Hospital Pharmacology
Introduction: Despite the core essence of sport, athletes often turn to doping substances to advance quickly and improve performance. Doping remains a critical issue in sports, undermining fair competition and athlete integrity. Methodology: A literature
Stojanović Dunja A., Pavlović Nebojša M., Strilić David Z., Đanić Maja P.   +3 more
doaj   +1 more source

Uricosuric diuretics

Kidney International, 1980
Elevation of the serum urate is well recognized as an invariable side effect of treatment with all diuretics except those agents, such as triamterene and amiloride, that retain potassium. Practitioners cannot fail to appreciate the frequency of hyperuricemia in many of their patients because, even in asymptomatic patients, it is regularly brought to ...
openaire   +3 more sources

Denosumab Offers Relatively Lower Initial Protection Against Osteoporotic Vertebral Fractures in Treatment‐Naive Patients Compared With Zoledronate

Clinical Pharmacology &Therapeutics, EarlyView.
We compared the initial efficacy of denosumab (Dmab) and zoledronate (ZOL) in treatment‐naive patients with osteoporosis. This cohort study, based on TriNetX data, evaluated the risks of fractures and mortality using Kaplan–Meier survival analyses, with hazard ratios (HRs) and 95% confidence intervals (CIs).
Ko‐Hsiu Lu, Shiow‐Ing Wang, Shun‐Fa Yang   +2 more
wiley   +1 more source