Results 61 to 70 of about 3,124,156 (300)
God, Determinism, and Action: Perspectives from Physics
Zygon, 2000 Recent articles by Michael Heller, Carl Helrich, Peter Hodgson, Jeffrey Koperski, and Nicholas Saunders present a challenge to much current thinking on God, divine action, and cosmology.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Benjamin and Spinoza: Divine Violence and Potentia
Eidos. A Journal for Philosophy of Culture, 2019 In this paper, I seek to clarify, criticize, and expand upon the ambiguous-yet-influential concept of divine violence introduced by Walter Benjamin’s “Zur Kritik der Gewalt”. I proceed in three parts: in the first, I outline Benjamin’s argument about the
Emerson R. Bodde
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
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IS PHYSICS FUNDAMENTAL? ROBERT RUSSELL ON DIVINE ACTION
Zygon, 2010 Robert Russell's theological work has been a helpful stimulus to the task of understanding the meaning of divine action and providence in the age of science.
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Role of Will in Divine Action in View of Islamic Philosophy [PDF]
حکمت اسرا, 2013 The present study seeks to investigate the issue of the relationship of Will and Devine Action according to the views of Islamic philosophers. Hence, it first explains the two terms Will and Devine Action lexically and conceptually; then, it deals with ...
Hossein Ramezani
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