Results 81 to 90 of about 348,820 (310)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Margaret Cavendish, Feminist Ethics, and the Problem of Evil [PDF]
, 2018 This paper argues that, although Margaret Cavendish’s main philosophical contributions are not in philosophy of religion, she makes a case for a defense of God, in spite of the worst sorts of harms being present in the world.
Hernandez, Jill
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
IS PHYSICS FUNDAMENTAL? ROBERT RUSSELL ON DIVINE ACTION
Zygon, 2010 Robert Russell's theological work has been a helpful stimulus to the task of understanding the meaning of divine action and providence in the age of science.
doaj +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Berkeley on Voluntary Motion: A Conservationist Account [PDF]
, 2018 A plausible reading of Berkeley’s view of voluntary motion is occasionalism; this, however, leads to a specious conclusion against his argument of human action.
Oda, Takaharu
core +1 more source
Molinism, Creature-types, and the Nature of Counterfactual Implication [PDF]
, 2012 Granting that there could be true subjunctive conditionals of libertarian freedom (SCLs), I argue (roughly) that there could be such conditionals only in connection with individual "possible creatures" (in contrast to types).
Murphy, Daniel
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Do the Results of Divine Actions Have Preceding Causes? [PDF]
, 2011 If God brings about an event in the universe, does it have a preceding cause? For example, if the universe began with the Big Bang and if God brought it about, did the Big Bang then have a preceding cause?
Wachter, Daniel von
core +1 more source
"... in God only one infinite act can be thought...": The Ambiguity of Divine Agency and the Diversity of Evil [PDF]
, 2015 The paper argues that God does not act but is creative activity, which helps to overcome evil by the possibilities of the good that it opens up for creatures in the face of ...
Dalferth, Ingolf U.
core +1 more source